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KRT84 Mouse anti-Human, Clone: OTI2D1, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA527415

Catalog No. PIMA527415


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Description

Description

The Keratin multigene family is made of ""soft"" epithelial cytokeratins and ""hard"" hair Keratins. While the epithelial cytokeratins are involved in the layering and formation of epithelia, the hair Keratins are responsible for creating nails and hair. There are two types of Keratins: the acidic class I Keratin proteins and the basic/neutral class II Keratin proteins. Keratin 84, also known as KRT84, HB4 or KRTHB4, is a 600 amino acid protein that is expressed in hair follicles. Keratin 84 is a basic/neutral type II Keratin protein which heterodimerizes with type I Keratins to create hair and nails. The gene encoding Keratin 84 maps to human chromosome 12 which encodes over 1,100 genes and comprises approximately 4.5% of the human genome. Chromosome 12 is associated with a variety of diseases and afflictions, including hypochondrogenesis, achondrogenesis and Kniest dysplasia.
Specifications

Specifications

KRT84
Monoclonal
1 mg/mL
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Q9NSB2
Cytokeratin-84; Keratin; type II cuticular Hb4; Keratin-84; Keratin84; Short name=K84; Type II hair keratin Hb4; Type-II keratin Kb24; KRT84; KRTHB4
Mouse
IgG1
100 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
3890
Immunohistochemistry (Paraffin)
OTI2D1
Unconjugated
KRT84
Liquid
KRT84
Full length human recombit protein of KRT84 produced in E.coli
Affinity Chromatography
RUO
Antibody
Monoclonal
Human
Documents
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