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Invitrogen™ KSHV ORF62 Monoclonal Antibody (5B7B6)
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Catalog No. PIMA514770
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100 μL
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Catalog No. Quantity
PIMA514770 100 μL
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Catalog No. PIMA514770 Supplier Invitrogen™ Supplier No. MA514770
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Description

Mouse Monoclonal Antibody

MA5-14770 targets KSHV ORF62 in indirect ELISA, IHC and WB applications and shows reactivity with Virus samples. The MA5-14770 immunogen is purified recombinant fragment of human KSHV ORF62 expressed in E. Coli.

Kaposi's sarcoma-associated herpesvirus (KSHV) belongs to the gamma-(2)-herpesvirus subfamily and has been closely linked to the Kaposi's sarcoma, primary effusion lymphoma (PEL) and multicentric Castleman's disease. The genome of KSHV is 165-170 kb and contains at least 88 open reading frames. At least five major proteins are likely to be involved in the assembly of the HHV-8 capsid, including a protease (encoded by ORF17), the major capsid protein (encoded by ORF25), and three other smaller capsid proteins (encoded by ORF62, ORF26, and ORF65). Previous structural studies have shown that the HSV-1 triplex is a monomer of VP19c and a dimer of VP23 and that the HCMV triplex is similarly composed of a monomer and a dimer. By analogy, the KSHV triplexes are likely also composed of a monomer of the ORF62 protein and a dimer of the ORF26 protein, which are the respective homologs of VP19c and VP23.
TRUSTED_SUSTAINABILITY

Specifications

Antigen KSHV ORF62
Applications ELISA, Immunohistochemistry, Western Blot, Immunocytochemistry
Classification Monoclonal
Clone 5B7B6
Concentration Conc. Not Determined
Conjugate Unconjugated
Formulation ascites with 0.03% sodium azide
Gene Alias Kaposi's Sarcoma Virus; Kaposi's sarcoma-associated herpesvirus
Host Species Mouse
Immunogen Purified recombinant fragment of human KSHV ORF62 expressed in E. Coli.
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Target Species Virus
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgM
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