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Invitrogen™ KSR1 Polyclonal Antibody
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Catalog No. PIPA5110765
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100 μL
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Catalog No. Quantity
PIPA5110765 100 μL
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Catalog No. PIPA5110765 Supplier Invitrogen™ Supplier No. PA5110765
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: SMIFGVKCKH CRLKCHNKCT KEAPACRISF LPLTRLRRTE SVPSDINNPV DRAAEPHFGT LPKALTKKEH PPAMNHLDSS SNPSSTTSST PSSPAPFPTS SNPSSATTPP NPSPGQRDSR FNFPA Highest antigen sequence indentity to the following orthologs: Rat - 95%, Mouse - 96%.

Part of a multiprotein signaling complex which promotes phosphorylation of Raf family members and activation of downstream MAP kinases. Independently of its kinase activity, acts as MAP2K1/MEK1 and MAP2K2/MEK2-dependent allosteric activator of BRAF; upon binding to MAP2K1/MEK1 or MAP2K2/MEK2, dimerizes with BRAF and promotes BRAF-mediated phosphorylation of MAP2K1/MEK1 and/or MAP2K2/MEK2 (PubMed:29433126). Promotes activation of MAPK1 and/or MAPK3, both in response to EGF and to cAMP. Its kinase activity is unsure. Some protein kinase activity has been detected in vitro, however the physiological relevance of this activity is unknown. [UniProt].
TRUSTED_SUSTAINABILITY

Specifications

Antigen KSR1
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 0.10 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene KSR1
Gene Accession No. Q8IVT5
Gene Alias AW492498; B-KSR1; CAP kinase; D11Bhm183e; D11Bhm184e; hb; HB protein; kinase KSR1; Kinase suppressor of Ras 1; Ksr; KSR1; mKSR1; OTTHUMP00000162931; protein Hb; RSU2
Gene Symbols KSR1
Host Species Rabbit
Immunogen Recombinant Protein corresonding to Human KSR1. Recombinant protein control fragment (Product #RP-89822).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 8844
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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