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Tocris Bioscience™ KT 182
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Catalog No. 673810
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67-381-0 10 mg
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Catalog No. 67-381-0 Supplier Tocris Bioscience™ Supplier No. 6738/10
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Description

Potent, selective and irreversible α/β-hydrolase domain 6 (ABHD6) inhibitor

KT 182 is a potent, selective and irreversible α/β-hydrolase domain 6 (ABHD6) inhibitor (IC50 = 1.7 nM). KT 182 exhibits selectively for ABHD6 over other brain and liver serine hydrolases, but does exhibit some activity at carboxylesterase-1. KT 182 inhibits ABHD6 activity in the brain and liver in mice following intraperitoneal administration.

Specifications

Chemical Name or Material [4-[3 '-(Hydroxymethyl)[1,1 '-biphenyl]-4-yl]-1 H-1,2,3-triazol-1-yl](2-phenyl-1-piperidinyl)methanone
CAS 1402612-62-7
Quantity 10 mg
Target Hydrolase Inhibitors
Molecular Formula C27H26N4O2
Purity 0.98
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