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KT 5823, Tocris Bioscience™
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Catalog No. 1289100U
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Quantity:
100 μg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

Selective protein kinase G inhibitor

Selective inhibitor of protein kinase G (Ki values are 0.23, 4 and > 10 μM for inhibition of PKG, PKC and PKA respectively). Inhibits SNP-stimulated PKG activity with an IC50 of 60 nM in dispersed smooth muscle cells and has little effect on PKA activity at concentrations of up to 10 μM.

Chemical Identifiers

CAS 126643-37-6
Molecular Formula C29H25N3O5
Molecular Weight (g/mol) 495.535
InChI Key QTYMDECKVKSGSM-NNZIQWQDSA-N
Synonym (9S,10R,12R)-2,3,9,10,11,12-Hexahydro-10-methoxy-2,9-dimethyl-1-oxo-9,12-epoxy-1H-diindolo[1,2,3-fg:3',2',1'-kl]pyrrolo[3,4-i][1,6]benzodiazocine-10-carboxylic acid, methyl ester
PubChem CID 101612238
SMILES CC12C(CC(O1)N3C4=CC=CC=C4C5=C6C(=C7C8=CC=CC=C8N2C7=C53)CN(C6=O)C)(C(=O)OC)OC

Specifications

Quantity 100 μg
Formula Weight 495.53
Percent Purity 95%
Chemical Name or Material KT 5823

Safety and Handling

Recommended Storage Desiccate at -20°C
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