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Invitrogen™ KT3 tag Polyclonal Antibody
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Catalog No. PIPA5118386
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100 μL
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PIPA5118386 100 μL
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Catalog No. PIPA5118386 Supplier Invitrogen™ Supplier No. PA5118386
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Description

Rabbit Polyclonal Antibody

This product is predicted to work in ELISA at a dilution of 1:10,000.

The KT3 tag does not correspond to a specific gene but is often used in biochemical and molecular biology research as a peptide tag for protein detection and purification. It is related to the PI3K/AKT/mTOR signaling pathway, which is a critical regulatory network in eukaryotic cells involved in cell survival, growth, and metabolism. The PI3K (phosphatidylinositol 3-kinase) enzyme generates phosphatidylinositol-3,4,5-trisphosphate (PI(3,4,5)P3), acting as a second messenger that facilitates the translocation and activation of Akt at the plasma membrane by phosphoinositide-dependent kinases. This pathway is frequently activated in various cancers, contributing to tumorigenesis and cancer progression by promoting cell growth and inhibiting apoptosis. Targeted therapies inhibiting this pathway are being studied for their potential in cancer treatment.
TRUSTED_SUSTAINABILITY

Specifications

Antigen KT3 tag
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.2% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4
Host Species Rabbit
Immunogen Recombinant protein fused with KT3 Tag.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Target Species Tag
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
Target Molecule Tag
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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