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Ku70/XRCC6 Mouse anti-Human, Primate, Chicken, Mouse, Rat, Alexa Fluor™ 532, Clone: KU729, Novus Biologicals™

Mouse Monoclonal Antibody

Manufacturer:  Novus Biologicals NBP234663AF532

Catalog No. NP234663A32

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Ku70/XRCC6 Monoclonal antibody specifically detects Ku70/XRCC6 in Human, Primate, Chicken, Mouse, Rat samples. It is validated for Immunocytochemistry, Immunofluorescence.


Conjugated, Purified
Nuclear extract of human HL-60 cells
Protein A purified
Breast Cancer, Cancer, DNA Double Strand Break Repair, DNA Repair, Non homologous end joining
Chicken, Human, Mouse, Primate, Rat
Immunocytochemistry, Immunofluorescence
Alexa Fluor™ 532
50 mM sodium borate with 0.05% sodium azide
5′-deoxyribose-5-phosphate lyase Ku70, 5′-dRP lyase Ku70, 70 kDa subunit of Ku antigen, ATP-dependent DNA helicase 2 subunit 1, ATP-dependent DNA helicase II 70 kDa subunit, CTC box binding factor 75 kDa subunit, CTC box-binding factor 75 kDa subunit, CTC75, CTCBF, D22S731, EC 3.6.4.-, EC 4.2.99.-, G22P1Ku70, Ku autoantigen p70 subunit, Ku autoantigen, 70kDa, KU70, ML8,70 kDa subunit, Thyroid-lupus autoantigen, thyroid-lupus autoantigen p70, TLAAD22S671, X-ray repair complementing defective repair in Chinese hamster cells 6DNA repair protein XRCC6, X-ray repair cross-complementing protein 6
IgG1 Kappa
0.1 mL
Store at 4°C in the dark.
Recognizes a dimer of two proteins of 70kDa and ~80kDa, identified as two subunits of Ku. This MAb recognizes a conformational epitope of p70/p80 dimer, which is destroyed during Western blotting. The p70/p80 dimer is important for function of a 460kDa DNA-dependent protein kinase. Ku protein plays a role in cell signaling, proliferation, DNA repair, replication, transcriptional activation, and apoptosis.
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