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KV3.2 (KCNC2) Mouse anti-Human, Mouse, Rat, Clone: S410-17, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA527683

Catalog No. PIMA527683


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Description

Description

Voltage-gated K+ channels in the plasma membrane control the repolarization and the frequency of action potentials in neurons, muscles and other excitable cells. The KV gene family encodes more than 30 proteins that comprise the subunits of the K+ channels. The subunits vary in their gating and permeation properties, subcellular distribution and expression patterns. Functional KV channels assemble as tetramers consisting of pore-forming alpha subunits, which include the KV1, KV2, KV3, KV4 and KV9 proteins, as well as accessory subunits that modify the gating properties of the coexpressed KV subunits. KV3.2 is a multipass membrane protein that regulates the voltage-dependent K+ permeability of excitable membranes. The tail of KV3.2 may be influential in the targeting of the channel to specific subcellular compartments and/or the regulation of channel activity.
Specifications

Specifications

KV3.2 (KCNC2)
Monoclonal
1 mg/ml
PBS with 50% glycerol and 0.1% sodium azide; pH 7.4
P22462, Q14B80, Q96PR1
Potassium voltage-gated channel subfamily C member 2, Kcnc2, KSHIIIA
Mouse
IgG1
100 μg
-20°C
Primary
246153, 268345, 3747
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (PFA fixed), Western Blot
S410-17
Unconjugated
KCNC2
Liquid
Kcnc2
Fusion protein amino acids 474-613 (Cytoplasmic C-terminus) of rat Kv3.2a
Protein G
RUO
Antibody
Monoclonal
Human, Mouse, Rat
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