KV3.2 (KCNC2) Mouse anti-Human, Mouse, Rat, Clone: S410-17, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA527683
DescriptionVoltage-gated K+ channels in the plasma membrane control the repolarization and the frequency of action potentials in neurons, muscles and other excitable cells. The KV gene family encodes more than 30 proteins that comprise the subunits of the K+ channels. The subunits vary in their gating and permeation properties, subcellular distribution and expression patterns. Functional KV channels assemble as tetramers consisting of pore-forming alpha subunits, which include the KV1, KV2, KV3, KV4 and KV9 proteins, as well as accessory subunits that modify the gating properties of the coexpressed KV subunits. KV3.2 is a multipass membrane protein that regulates the voltage-dependent K+ permeability of excitable membranes. The tail of KV3.2 may be influential in the targeting of the channel to specific subcellular compartments and/or the regulation of channel activity.
|PBS with 50% glycerol and 0.1% sodium azide; pH 7.4|
|P22462, Q14B80, Q96PR1|
|Potassium voltage-gated channel subfamily C member 2, Kcnc2, KSHIIIA|
|246153, 268345, 3747|
|Immunocytochemistry, Immunofluorescence, Immunohistochemistry (PFA fixed), Western Blot|
|Fusion protein amino acids 474-613 (Cytoplasmic C-terminus) of rat Kv3.2a|
|Human, Mouse, Rat|
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