Invitrogen™ KV4.2 (KCND2) Polyclonal Antibody

Rabbit Polyclonal Antibody

Catalog Number	Mfr. No.	Quantity
PIPA5110970	Invitrogen™ PA5110970	100 μL

Description

Immunogen sequence: GSIQELSTIQ IRCVERTPLS NSRSSLNAKM EECVKLNCEQ PYVTTAIISI PTPPVTTPEG DDRPESPEYS GGNIVRVSA.

Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes-shaker, shaw, shab, and shal-have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shal-related subfamily, members of which form voltage-activated A-type potassium ion channels and are prominent in the repolarization phase of the action potential. This member mediates a rapidly inactivating, A-type outward potassium current which is not under the control of the N terminus as it is in Shaker channels.

Specifications

• Antigen: KV4.2 (KCND2)
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Classification: Polyclonal
• Form: Liquid
• Isotype: IgG
• Target Species: Human
• Gene: KCND2
• Gene Alias: AI839615; AW555701; KCND2; KIAA1044; KV4.2; mKIAA1044; MNCb-7013; potassium channel alpha subunit Kv4.2; potassium channel Kv4.2; potassium channel, voltage gated Shal related subfamily D, member 2; potassium channel, voltage-gated Shal-related subfamily D, member 2; potassium voltage gated channel, Shal-related family, member 2; potassium voltage-gated channel subfamily D member 2; potassium voltage-gated channel, Shal-related family, member 2; potassium voltage-gated channel, Shal-related subfamily, member 2; R75121; RK5; Shal1; voltage-gated potassium channel; voltage-gated potassium channel subunit Kv4.2; voltage-sensitive potassium channel
• Gene Symbols: KCND2
• Primary or Secondary: Primary
• Purification Method: Antigen affinity chromatography

• Concentration: 0.10 mg/mL
• Applications: Immunohistochemistry (Paraffin)
• Conjugate: Unconjugated
• Host Species: Rabbit
• Regulatory Status: RUO
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q9NZV8
• Gene ID (Entrez): 3751
• Immunogen: Recombinant Protein corresonding to Human KV4.2 (KCND2). Recombinant protein control fragment (Product #RP-91287).
• Product Type: Antibody