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Invitrogen™ KV4.2 (KCND2) Polyclonal Antibody
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Catalog No. PIPA5110970
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100 μL
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PIPA5110970 100 μL
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Catalog No. PIPA5110970 Supplier Invitrogen™ Supplier No. PA5110970
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: GSIQELSTIQ IRCVERTPLS NSRSSLNAKM EECVKLNCEQ PYVTTAIISI PTPPVTTPEG DDRPESPEYS GGNIVRVSA Highest antigen sequence indentity to the following orthologs: Mouse - 99%, Rat - 49%.

Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes-shaker, shaw, shab, and shal-have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shal-related subfamily, members of which form voltage-activated A-type potassium ion channels and are prominent in the repolarization phase of the action potential. This member mediates a rapidly inactivating, A-type outward potassium current which is not under the control of the N terminus as it is in Shaker channels.
TRUSTED_SUSTAINABILITY

Specifications

Antigen KV4.2 (KCND2)
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 0.10 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene KCND2
Gene Accession No. Q9NZV8
Gene Alias AI839615; AW555701; KCND2; KIAA1044; KV4.2; mKIAA1044; MNCb-7013; potassium channel alpha subunit Kv4.2; potassium channel Kv4.2; potassium channel, voltage gated Shal related subfamily D, member 2; potassium channel, voltage-gated Shal-related subfamily D, member 2; potassium voltage gated channel, Shal-related family, member 2; potassium voltage-gated channel subfamily D member 2; potassium voltage-gated channel, Shal-related family, member 2; potassium voltage-gated channel, Shal-related subfamily, member 2; R75121; RK5; Shal1; voltage-gated potassium channel; voltage-gated potassium channel subunit Kv4.2; voltage-sensitive potassium channel
Gene Symbols KCND2
Host Species Rabbit
Immunogen Recombinant Protein corresonding to Human KV4.2 (KCND2). Recombinant protein control fragment (Product #RP-91287).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3751
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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