Invitrogen™ KV4.3 (KCND3) Polyclonal Antibody

Catalog No.	Quantity
PIPA556151	100 μL

Catalog No. PIPA556151 Supplier Invitrogen™ Supplier No. PA556151

Description

Rabbit Polyclonal Antibody

Immunogen sequence: NYPSTRSPSL SSHPGLTTTC CSRRSKKTTH LPNSNLPATR LRSMQELSTI HIQGSEQPSL TTSRSSLNLK ADDGLRPNCK TSQITTAIIS IPTPPALTPE GESRPPPASP GPNTNIPSIA SNVVKVS Highest antigen sequence identity to the following orthologs: Mouse - 98%, Rat - 98%.

Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shal-related subfamily, members of which form voltage-activated A-type potassium ion channels and are prominent in the repolarization phase of the action potential. This member includes two isoforms with different sizes, which are encoded by alternatively spliced transcript variants of this gene.

Specifications

• Antigen: KV4.3 (KCND3)
• Applications: Immunohistochemistry (Paraffin)
• Classification: Polyclonal
• Concentration: 0.2 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene: KCND3
• Gene Accession No.: Q9UK17
• Gene Alias: AW045978; BRGDA9; KCND3; KCND3L; KCND3S; Kncd3; KSHIVB; KV4.3; potassium channel alpha subunit Kv4.3 short form; potassium channel Kv4.3; potassium channel Kv4.3L; potassium channel Kv4.3M; potassium channel, voltage gated Shal related subfamily D, member 3; potassium channel, voltage-gated Shal-related subfamily D, member 3; potassium ionic channel Kv4.3; potassium voltage gated channel, Shal-related family, member 3; potassium voltage-gated channel long; potassium voltage-gated channel subfamily D member 3; potassium voltage-gated channel, Shal-related family, member 3; potassium voltage-gated channel, Shal-related subfamily, member 3; SCA19; SCA22; sha1-related potassium channel Kv4.3; voltage-gated K+ channel; voltage-gated potassium channel subunit Kv4.3
• Gene Symbols: KCND3
• Host Species: Rabbit
• Immunogen: Recombinant protein corresponding to Human KCND3. Recombinant protein control fragment (Product #RP-91276).
• Purification Method: Antigen affinity chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 3752
• Target Species: Human
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG