Invitrogen™ KV4.3 (KCND3) Polyclonal Antibody

Catalog No.	Quantity
PIPA593292	100 μL

Catalog No. PIPA593292 Supplier Invitrogen™ Supplier No. PA593292

Description

Rabbit Polyclonal Antibody

Immunogen sequence: MESSMQNYPS TRSPSLSSHP GLTTTCCSRR SKKTTHLPNS NLPATRLRSM QELSTIHIQG SEQPSLTTSR SSLNLKADDG LRPNCKTSQI TTAIISIPTP PALTPEGESR PPPASPGPNT NIPSIASNVV KVSAL; Positive Samples: Mouse liver, Mouse brain, Rat liver; Cellular Location: Cell membrane, Cell projection, Membrane, Multi-pass membrane protein, dendrite, sarcolemma.

Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shal-related subfamily, members of which form voltage-activated A-type potassium ion channels and are prominent in the repolarization phase of the action potential. This member includes two isoforms with different sizes, which are encoded by alternatively spliced transcript variants of this gene.

Specifications

• Antigen: KV4.3 (KCND3)
• Applications: ELISA, Immunohistochemistry (Paraffin), Western Blot
• Classification: Polyclonal
• Concentration: 8.17 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene: KCND3
• Gene Accession No.: Q62897, Q9UK17, Q9Z0V1
• Gene Alias: AW045978; BRGDA9; KCND3; KCND3L; KCND3S; Kncd3; KSHIVB; KV4.3; potassium channel alpha subunit Kv4.3 short form; potassium channel Kv4.3; potassium channel Kv4.3L; potassium channel Kv4.3M; potassium channel, voltage gated Shal related subfamily D, member 3; potassium channel, voltage-gated Shal-related subfamily D, member 3; potassium ionic channel Kv4.3; potassium voltage gated channel, Shal-related family, member 3; potassium voltage-gated channel long; potassium voltage-gated channel subfamily D member 3; potassium voltage-gated channel, Shal-related family, member 3; potassium voltage-gated channel, Shal-related subfamily, member 3; SCA19; SCA22; sha1-related potassium channel Kv4.3; voltage-gated K+ channel; voltage-gated potassium channel subunit Kv4.3
• Gene Symbols: KCND3
• Host Species: Rabbit
• Immunogen: Recombinant protein (or fragment)
• Purification Method: Affinity Chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 3752, 56543, 65195
• Target Species: Human, Mouse, Rat
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov