Invitrogen™ KV4.3 (KCND3) Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA595211

Catalog No. PIPA595211

Description

Human Kv4.3 shares 100% and 99% amino acid (aa) sequences identity with mouse and rat Kv4.3, respectively. Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 μg/mL. Positive Control - WB: Mouse Brain Tissue. Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shal-related subfamily, members of which form voltage-activated A-type potassium ion channels and are prominent in the repolarization phase of the action potential. This member includes two isoforms with different sizes, which are encoded by alternatively spliced transcript variants of this gene.

Specifications

• Antigen: KV4.3 (KCND3)
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: KCND3
• Gene Alias: AW045978; BRGDA9; KCND3; KCND3L; KCND3S; Kncd3; KSHIVB; KV4.3; potassium channel alpha subunit Kv4.3 short form; potassium channel Kv4.3; potassium channel Kv4.3L; potassium channel Kv4.3M; potassium channel, voltage gated Shal related subfamily D, member 3; potassium channel, voltage-gated Shal-related subfamily D, member 3; potassium ionic channel Kv4.3; potassium voltage gated channel, Shal-related family, member 3; potassium voltage-gated channel long; potassium voltage-gated channel subfamily D member 3; potassium voltage-gated channel, Shal-related family, member 3; potassium voltage-gated channel, Shal-related subfamily, member 3; SCA19; SCA22; sha1-related potassium channel Kv4.3; voltage-gated K+ channel; voltage-gated potassium channel subunit Kv4.3
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 3752, 56543
• Content And Storage: -20°C
• Form: Lyophilized

• Applications: Western Blot
• Concentration: 500 μg/mL
• Formulation: PBS with 5mg BSA and 0.05mg sodium azide
• Gene Accession No.: Q9UK17, Q9Z0V1
• Gene Symbols: KCND3
• Immunogen: E.coli-derived human Kv4.3 recombinant protein (Position: M1-H177).
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG