Invitrogen™ KVbeta2 (KCNAB2) Polyclonal Antibody

Catalog No.	Quantity
PIPA5115447	100 μL

Catalog No. PIPA5115447 Supplier Invitrogen™ Supplier No. PA5115447

Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total KCNAB2.

Kcnab2 is a voltage-gated potassium channels (KV) belong to the 6-TM family of potassium channel that also comprises the Ca2+-activated Slo (actually 7-TM) and the Ca2+-activated SK subfamilies. The alpha-subunits contain a single pore-forming region and combine to form tetramers. Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. The diverse functions of potassium channels include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). Kcnab2 is one of the beta subunits, which are auxiliary proteins associating with functional Kv-alpha subunits. Alternative splicing of the Kcnab2 gene results in multiple transcript variants encoding distinct isoforms. Diseases associated with KCNAB2 include Chromosome 1P36 Deletion Syndrome.

Specifications

• Antigen: KVbeta2 (KCNAB2)
• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Classification: Polyclonal
• Concentration: 1 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 50% glycerol and 0.02% sodium azide
• Gene: KCNAB2
• Gene Accession No.: P62482, P62483, Q13303
• Gene Alias: AKR6A5; Ckbeta2; F5; HKvbeta2; HKvbeta2.1; HKvbeta2.2; I2rf5; K(+) channel subunit beta-2; KCNA2B; KCNAB2; KCNAB2.1; KCNAB2.2; Kcnb3; KCNK2; KVB2; Kvbeta2; Kv-beta-2; Kvbeta2.1; Kvbeta2.2; neuroimmune protein F5; potassium channel; potassium channel Kv beta 2.1 subunit; potassium channel Kv beta 2.2 subunit; potassium channel, voltage gated shaker-related subfamily A regulatory beta subunit 2; potassium channel, voltage gated subfamily A regulatory beta subunit 2; potassium channel, voltage-gated shaker-related subfamily A regulatory beta subunit 2; potassium voltage gated channel, shaker related subfamily, beta member 2; potassium voltage-gated channel subfamily A regulatory beta subunit 2; potassium voltage-gated channel, shaker-related subfamily, beta member 2; potassium voltage-gated channel, shaker-related subfamily, beta member 2, transcript variant 1; potassium voltage-gated channel, shaker-related subfamily, beta member 2, transcript variant 2; voltage-gated potassium channel subunit beta-2
• Gene Symbols: KCNAB2
• Host Species: Rabbit
• Immunogen: A synthesized peptide derived from human KCNAB2(Accession Q13303), corresponding to amino acid residues M1-C51.
• Purification Method: Affinity chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 16498, 29738, 8514
• Target Species: Human, Mouse, Rat
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov