Invitrogen™ KYNU Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA522379

Catalog No. PIPA522379

Description

Recommended positive controls: A549. Predicted reactivity: Mouse (88%), Rat (88%), Bovine (89%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Kynureninase is a pyridoxal-5'-phosphate (pyridoxal-P) dependent enzyme that catalyzes the cleavage of L-kynurenine and L-3-hydroxykynurenine into anthranilic and 3-hydroxyanthranilic acids, respectively. Kynureninase is involved in the biosynthesis of NAD cofactors from tryptophan through the kynurenine pathway. Kynureninase is a pyridoxal-5'-phosphate (pyridoxal-P) dependent enzyme that catalyzes the cleavage of L-kynurenine and L-3-hydroxykynurenine into anthranilic and 3-hydroxyanthranilic acids, respectively. Kynureninase is involved in the biosynthesis of NAD cofactors from tryptophan through the kynurenine pathway. Two transcript variants encoding different isoforms have been found for this gene. Kynureninase is a pyridoxal-5'-phosphate (pyridoxal-P) dependent enzyme that catalyzes the cleavage of L-kynurenine and L-3-hydroxykynurenine into anthranilic and 3-hydroxyanthranilic acids, respectively. Kynureninase is involved in the biosynthesis of NAD cofactors from tryptophan through the kynurenine pathway. Two transcript variants encoding different isoforms have been found for this gene.

Specifications

• Antigen: KYNU
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Kynu
• Gene Alias: 4432411A05Rik; HAMAP-Rule:MF_03017}; KYNU; kynureninase; kynureninase (L-kynurenine hydrolase); kynureninase {ECO:0000255; kynureninase-like protein; KYNUU; L-kynurenine hydrolase; L-kynurenine hydrolase {ECO:0000255
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 8942
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.63 mg/mL
• Formulation: 0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: Q16719
• Gene Symbols: Kynu
• Immunogen: Recombinant protein encompassing a sequence within the center region of human KYNU. The exact sequence is proprietary.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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