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  5. Tocris Bioscience™ L-733,060 hydrochloride

Tocris Bioscience™ L-733,060 hydrochloride
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Catalog No. 114510
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Catalog No. Quantity
11-451-0 10 mg
11-455-0 50 mg
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Catalog No. 11-451-0 Supplier Tocris Bioscience™ Supplier No. 1145/10
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Description

Potent NK1 antagonist

Potent NK1 antagonist (Ki values are 0.08, 0.2 and 93.13 nM for gerbil, human and rat receptors, respectively). Produces anxiolytic-like effects in the gerbil elevated plus-maze. Exhibits antitumor activity in vitro. Also decreases HER2 activity and tumor growth in mice bearing HER2+ or EGFR+ breast tumors. Orally bioavailable and brain penetrant.

Chemical Identifiers

CAS 148687-76-7
Molecular Formula C20H20ClF6NO

Specifications

Quantity 10 mg
Formula Weight 439.83
Purity >99%
Molecular Weight (g/mol) 439.83
Chemical Name or Material L-733, 060 hydrochloride

Safety and Handling

Recommended Storage Store at Room Temperature
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