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L-733,060 hydrochloride, Tocris Bioscience™ Available on GSA/VA Contract for Federal Government customers only.

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Quantity:
10mg
50mg
148687-76-7
C20H20ClF6NO
439.826
DYEUTIUITGHIEO-APTPAJQOSA-N
(2S, 3S)-3-[[3, 5-bis(Trifluoromethyl)phenyl]methoxy]-2-phenylpiperidine hydrochloride
11957600
(2S,3S)-3-[[3,5-bis(trifluoromethyl)phenyl]methoxy]-2-phenylpiperidine;hydrochloride
C1CC(C(NC1)C2=CC=CC=C2)OCC3=CC(=CC(=C3)C(F)(F)F)C(F)(F)F.Cl
148687-76-7
C20H20ClF6NO
439.826
DYEUTIUITGHIEO-APTPAJQOSA-N
(2S, 3S)-3-[[3, 5-bis(Trifluoromethyl)phenyl]methoxy]-2-phenylpiperidine hydrochloride
11957600
(2S,3S)-3-[[3,5-bis(trifluoromethyl)phenyl]methoxy]-2-phenylpiperidine;hydrochloride
C1CC(C(NC1)C2=CC=CC=C2)OCC3=CC(=CC(=C3)C(F)(F)F)C(F)(F)F.Cl

Potent NK1 antagonist

Potent NK 1 antagonist (K i values are 0.08, 0.2 and 93.13 nM for gerbil, human and rat receptors, respectively). Produces anxiolytic-like effects in the gerbil elevated plus-maze. Exhibits antitumor activity in vitro. Also decreases HER2 activity and tumor growth in mice bearing HER2 + or EGFR + breast tumors. Orally bioavailable and brain penetrant.

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Quantity 50mg
Formula Weight 439.83
Percent Purity >99%
Chemical Name or Material L-733, 060 hydrochloride

Recommended Storage : Store at Room Temperature