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  7. L-733,060 hydrochloride, Tocris Bioscience™

L-733,060 hydrochloride, Tocris Bioscience™

Catalog Number 114550
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Quantity:
10 mg
50 mg
This item is not returnable. View return policy
148687-76-7
C20H20ClF6NO
439.83
MFCD05865535
DYEUTIUITGHIEO-UHFFFAOYNA-N
(2S, 3S)-3-[[3, 5-bis(Trifluoromethyl)phenyl]methoxy]-2-phenylpiperidine hydrochloride
11957600
3-{[3,5-bis(trifluoromethyl)phenyl]methoxy}-2-phenylpiperidine hydrochloride
Cl.FC(F)(F)C1=CC(=CC(COC2CCCNC2C2=CC=CC=C2)=C1)C(F)(F)F
This item is not returnable. View return policy
148687-76-7
C20H20ClF6NO
439.83
MFCD05865535
DYEUTIUITGHIEO-UHFFFAOYNA-N
(2S, 3S)-3-[[3, 5-bis(Trifluoromethyl)phenyl]methoxy]-2-phenylpiperidine hydrochloride
11957600
3-{[3,5-bis(trifluoromethyl)phenyl]methoxy}-2-phenylpiperidine hydrochloride
Cl.FC(F)(F)C1=CC(=CC(COC2CCCNC2C2=CC=CC=C2)=C1)C(F)(F)F

Description

Potent NK1 antagonist

Potent NK1 antagonist (Ki values are 0.08, 0.2 and 93.13 nM for gerbil, human and rat receptors, respectively). Produces anxiolytic-like effects in the gerbil elevated plus-maze. Exhibits antitumor activity in vitro. Also decreases HER2 activity and tumor growth in mice bearing HER2+ or EGFR+ breast tumors. Orally bioavailable and brain penetrant.
Quantity 50 mg
Formula Weight 439.83
Percent Purity >99%
Chemical Name or Material L-733, 060 hydrochloride

Safety and Handling

Recommended Storage Store at Room Temperature
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