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Tocris Bioscience™ L-755,507
GSA_VA

Catalog No. 219710
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Catalog No. Quantity
21-971-0 10 mg
21-975-0 50 mg
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Catalog No. 21-971-0 Supplier Tocris Bioscience™ Supplier No. 2197/10
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Description

Very potent and selective β3 partial agonist

L-755,507 is a potent β3-adrenergic receptor partial agonist > 1000-fold selective over β1- and β2-adrenoceptors (EC50 values are 0.43, 580 and > 10000 nM for activation of cloned human β3-, β1- and β2-adrenoceptors respectively). Stimulates lipolysis in rhesus adipocytes in vitro (EC50 = 3.9 nM). Enhances CRISPR-mediated homology-directed repair (HDR) efficiency 2-3-fold for large fragments and ∽9-fold for point mutations, in human induced pluripotent stem cells (iPSCs).

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Specifications

Quantity 10 mg
Product Type L-755,507
Purity >98%
Molecular Weight (g/mol) 584.73
Inhibitors L-755,507

For Research Use Only

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