Invitrogen™ L-Plastin Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA597918

Catalog No. PIPA597918

Description

L-Plastin Polyclonal Antibody for Western Blot, IHC (P), IP, ELISA

L-plastin is a leukocyte specific actin bundling protein from fimbrin family of proteins. It has two actin-binding domains and two EF hand type calcium-binding domains. It gets phosphorylated on the serine residue in its headpiece region in response to a variety of inflammatory stimuli. It is hypothesized that L-plastin may play a role in regulating integrin mediated adhesion in leukocytes. L-plastin is expressed in majority of human cancer cell lines derived from solid tumors. Its expression is positively upregulated by testosterones in androgen receptor positive prostrate and breast cancer cells through three androgen receptor binding elements located in the upstream region of the gene.

Specifications

• Antigen: L-Plastin
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: LCP1
• Gene Alias: 65 kDa macrophage protein; AW536232; bA139H14.1 (lymphocyte cytosolic protein 1 (L-plastin)); cb245; CP64; D14Ertd310e; DKFZp781A23186; epididymis secretory protein Li 37; fj24b12; FLJ25423; FLJ26114; FLJ39956; HEL-S-37; LC64P; LCP1; LCP-1; leucocyte-specific plastin 1; L-fimbrin; LPL; L-plastin; L-plastin (Lymphocyte cytosolic protein 1) (LCP-1) (65 kDa macrophage protein) (PP65); L-plastin (Lymphocyte cytosolic protein 1) (LCP-1) (LC64P); lymphocyte cytosolic plastin 1; lymphocyte cytosolic protein 1; lymphocyte cytosolic protein 1 (L-plastin); Lymphocyte cytosolic protein-1 (plasmin); plastin 2; plastin 2, L; plastin-2; Pls2; pp65; wu:fj24b12
• Host Species: Rabbit
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 3936
• Content And Storage: -20°C or -80°C if preferred
• Form: Liquid

• Applications: ELISA, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
• Concentration: 2.665 mg/mL
• Formulation: PBS with 50% glycerol and 0.03% ProClin 300; pH 7.4
• Gene Accession No.: P13796
• Gene Symbols: LCP1
• Immunogen: Recombinant Human Plastin-2 protein (2-627AA).
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG