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Invitrogen™ L-Plastin Polyclonal Antibody
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Catalog No. PIPA5116345
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400 μL
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PIPA5116345 400 μL
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Catalog No. PIPA5116345 Supplier Invitrogen™ Supplier No. PA5116345
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Rabbit Polyclonal Antibody

L-Plastin Polyclonal Antibody for Western Blot

L-plastin is a leukocyte specific actin bundling protein from fimbrin family of proteins. It has two actin-binding domains and two EF hand type calcium-binding domains. It gets phosphorylated on the serine residue in its headpiece region in response to a variety of inflammatory stimuli. It is hypothesized that L-plastin may play a role in regulating integrin mediated adhesion in leukocytes. L-plastin is expressed in majority of human cancer cell lines derived from solid tumors. Its expression is positively upregulated by testosterones in androgen receptor positive prostrate and breast cancer cells through three androgen receptor binding elements located in the upstream region of the gene.
TRUSTED_SUSTAINABILITY

Specifications

Antigen L-Plastin
Applications Western Blot
Classification Polyclonal
Concentration 0.45 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.09% sodium azide; pH 7.4
Gene LCP1
Gene Accession No. P13796, Q6P698
Gene Alias 65 kDa macrophage protein; AW536232; bA139H14.1 (lymphocyte cytosolic protein 1 (L-plastin)); cb245; CP64; D14Ertd310e; DKFZp781A23186; epididymis secretory protein Li 37; fj24b12; FLJ25423; FLJ26114; FLJ39956; HEL-S-37; LC64P; LCP1; LCP-1; leucocyte-specific plastin 1; L-fimbrin; LPL; L-plastin; L-plastin (Lymphocyte cytosolic protein 1) (LCP-1) (65 kDa macrophage protein) (PP65); L-plastin (Lymphocyte cytosolic protein 1) (LCP-1) (LC64P); lymphocyte cytosolic plastin 1; lymphocyte cytosolic protein 1; lymphocyte cytosolic protein 1 (L-plastin); Lymphocyte cytosolic protein-1 (plasmin); plastin 2; plastin 2, L; plastin-2; Pls2; pp65; wu:fj24b12
Gene Symbols LCP1
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide between 138-172 amino acids from the N-terminal region of human (DANRE) lcp1.
Purification Method Antigen affinity chromatography, Protein A
Quantity 400 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 30583, 3936
Target Species Human, Zebrafish
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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WARNING: Cancer - www.P65Warnings.ca.gov
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