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L-Plastin Rabbit anti-Human, Mouse, Polyclonal, Proteintech
SDP

Catalog No. 501736057 Shop All Proteintech Group Inc Products
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50-173-6057 150 μL
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Catalog No. 50-173-6057 Supplier Proteintech Group Inc Supplier No. 552081AP150UL
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Description

Rabbit Polyclonal Antibody

L-plastin is a leukocyte specific actin bundling protein from fimbrin family of proteins. It has two actin-binding domains and two EF hand type calcium-binding domains. It gets phosphorylated on the serine residue in its headpiece region in response to a variety of inflammatory stimuli. It is hypothesized that L-plastin may play a role in regulating integrin mediated adhesion in leukocytes. L-plastin is expressed in majority of human cancer cell lines derived from solid tumors. Its expression is positively upregulated by testosteronse in andrgen receptor positive prostrate and breast cancer cells through three androgen receptor binding elements located in the upstream region of the gene.

Specifications

Antigen L-Plastin
Applications Immunocytochemistry, Immunofluorescence, Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene LCP1
Gene Accession No. P13796, Q61233
Gene Alias L PLASTIN, LCP 1, LCP1, LPL, Lymphocyte cytosolic protein 1, Plastin 2, PLS2
Gene Symbols Lcp1
Host Species Rabbit
Immunogen Peptide
Purification Method Antigen Affinity Chromatography
Quantity 150 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 18826, 3936
Target Species Human, Mouse
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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