L1CAM Monoclonal Antibody (OTI1D12), TrueMAB™, OriGene

Catalog No.	Quantity
50-167-2584	100 μL
50-254-2281	30 μL

Catalog No. 50-167-2584 Supplier OriGene Supplier No. TA501440

Description

Mouse Monoclonal Antibody

L1CAM (CD171) is an axonal glycoprotein belonging to the immunoglobulin supergene family. The ectodomain, consisting of several immunoglobulin-like domains and fibronectin-like repeats (type III), is linked via a single transmembrane sequence to a conserved cytoplasmic domain. This cell adhesion molecule plays an important role in nervous system development, including neuronal migration and differentiation. Mutations in the gene cause three X-linked neurological syndromes known by the acronym CRASH (corpus callosum hypoplasia, retardation, aphasia, spastic paraplegia and hydrocephalus). Alternative splicing of a neuron-specific exon is thought to be functionally relevant.

Specifications

• Antigen: L1CAM
• Applications: Flow Cytometry, Immunocytochemistry, Immunofluorescence, Western Blot
• Classification: Monoclonal
• Clone: OTI1D12
• Concentration: 0.7 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
• Gene: L1CAM
• Gene Accession No.: P32004
• Gene Alias: CAML1, CD171, HSAS, HSAS1, MASA, MIC5, N-CAM-L1, N-CAML1, NCAM-L1, S10, SPG1
• Gene Symbols: L1CAM
• Host Species: Mouse
• Immunogen: Full length human recombit protein of human L1CAM produced in HEK293T cell.
• Purification Method: Affinity Chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 3897
• Target Species: Human
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG1