Invitrogen™ L2HGDH Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA564221

Catalog No. PIPA564221

Description

Immunogen sequence: KKEPYCRGLM AIDCPHTGIV DYRQVALSFA QDFQEAGGSV LTNFEVKGIE MAKESPSRSI DGMQYPIVIK NTKGEEI Highest antigen sequence identity to the following orthologs: Mouse - 81%, Rat - 78%.

This gene encodes L-2-hydroxyglutarate dehydrogenase, a FAD-dependent enzyme that oxidizes L-2-hydroxyglutarate to alpha-ketoglutarate in a variety of mammalian tissues. Mutations in this gene cause L-2-hydroxyglutaric aciduria, a rare autosomal recessive neurometabolic disorder resulting in moderate to severe mental retardation.

Specifications

• Antigen: L2HGDH
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: L2HGDH
• Gene Alias: 2-hydroxyglutarate dehydrogenase; alpha-hydroxyglutarate oxidoreductase; alpha-ketoglutarate reductase; BC016226; C14orf160; Duranin; FLJ12618; L2HGA; L2HGDH; L-2-hydroxyglutarate dehydrogenase; L-2-hydroxyglutarate dehydrogenase, mitochondrial; L-alpha-hydroxyglutarate dehydrogenase; RGD1306250
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 79944
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Immunocytochemistry
• Concentration: 0.4 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q9H9P8
• Gene Symbols: L2HGDH
• Immunogen: Recombinant protein corresponding to Human L2HGDH. Recombinant protein control fragment (Product #RP-104004).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG