Invitrogen™ L2HGDH Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5104318

Catalog No. PIPA5104318

Description

Antibody detects endogenous levels of total L2HGDH.

This gene encodes L-2-hydroxyglutarate dehydrogenase, a FAD-dependent enzyme that oxidizes L-2-hydroxyglutarate to alpha-ketoglutarate in a variety of mammalian tissues. Mutations in this gene cause L-2-hydroxyglutaric aciduria, a rare autosomal recessive neurometabolic disorder resulting in moderate to severe mental retardation.

Specifications

• Antigen: L2HGDH
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: L2HGDH
• Gene Alias: 2-hydroxyglutarate dehydrogenase; alpha-hydroxyglutarate oxidoreductase; alpha-ketoglutarate reductase; BC016226; C14orf160; Duranin; FLJ12618; L2HGA; L2HGDH; L-2-hydroxyglutarate dehydrogenase; L-2-hydroxyglutarate dehydrogenase, mitochondrial; L-alpha-hydroxyglutarate dehydrogenase; RGD1306250
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 217666, 314196, 79944
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: Q91YP0, Q9H9P8
• Gene Symbols: L2HGDH
• Immunogen: A synthesized peptide derived from human L2HGDH(Accession Q9H9P8), corresponding to amino acid residues P276-G326.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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