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Invitrogen™ L3MBTL1 Polyclonal Antibody
Rabbit Polyclonal Antibody
Supplier: Invitrogen™ PA5113645
Description
Immunogen sequence: RRREGHGTDS EMGQGPVRES QSSDPPALQF RISEYKPLNM AGVEQPPSPE For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles. Predicted homology: Dog: 92%; Guinea Pig: 77%; Human: 100%.
L3MBTL1 is the homolog of a protein identified in Drosophila as a suppressor of malignant transformation of neuroblasts and ganglion-mother cells in the optic centers of the brain. L3MBTL1 is localized to condensed chromosomes in mitotic cells and overexpression of this protein in a glioma cell line results in improper nuclear segregation and cytokinesis producing multinucleated cells. L3MBTL1 represents a polycomb group gene the encoded protein functions to regulate gene activity, likely via chromatin modification. Polycomb group protein specifically recognizes and binds mono- and dimethyllysine residues on target proteins, thereby acting as a reader of a network of post-translational modifications. Alternatively spliced transcript variants encoding different isoforms of the L3MBTL1 gene have been identified.
Specifications
L3MBTL1 | |
Polyclonal | |
Unconjugated | |
L3MBTL1 | |
C630004G01; dJ138B7.3; H-l(3)mbt; H-l(3)mbt protein; Kiaa0681; L(3)mbt protein homolog; l(3)mbt-like (Drosophila); l(3)mbt-like 1; l(3)mbt-like 1 (Drosophila); L3mbt; L3MBTL; L3MBTL histone methyl-lysine binding protein 1; L3MBTL1; L3MBTL1, histone methyl-lysine binding protein; lethal (3) malignant brain tumor l(3); lethal(3)malignant brain tumor-like protein 1; lethal(3)malignant brain tumor-like protein 1; serine/threonine-protein kinase Sgk2; LOC100070683; mKIAA0681; RGD1307316; RP1-138B7.1; ZC2HC3 | |
Rabbit | |
Affinity Chromatography | |
RUO | |
26013 | |
-20°C, Avoid Freeze/Thaw Cycles | |
Liquid |
Western Blot | |
0.5 mg/mL | |
PBS with 2% sucrose and 0.09% sodium azide | |
Q9Y468 | |
L3MBTL1 | |
Synthetic peptide directed towards the N terminal region of human L3MBTL. | |
100 μL | |
Primary | |
Human | |
Antibody | |
IgG |
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