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Epredia™ Lab Vision™ Actin, Smooth Muscle, Ab-1 Mouse Monoclonal Antibody, 40μg/mL, BSA and azide

Catalog No. MS1143P1ABX Shop All Epredia Products
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Quantity:
100 μL
200 μL
500 μL
1 mL
Concentration:
1mg/mL
200μg/mL
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Catalog No. Quantity Concentration
MS1143P1ABX 100 μL 1mg/mL
MS1143P0 100 μL 200μg/mL
MS1143P1 500 μL 200μg/mL
MS1143P 1 mL 200μg/mL
MS1143PABX 200 μL 1mg/mL
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Catalog No. MS1143P1ABX Supplier Epredia™ Supplier No. MS1143P1ABX

Description

Ensure accurate, reproducible results in western blotting and immunoprecipitation experiments with Epredia™ Caspase 8 (FLICE) Ab-3, Mouse Monoclonal Antibody.

Caspase 8 binds to the death effector domain (DED) of FADD through an analogous DED domain present in tandem in the proform of the caspase 8 protein. Recruitment of caspase 8 to the Fas receptor results in oligomerization of the caspase 8 protein, which in turn drives its autoactivation through “self-cleavage”. Activated caspase 8 then activates other downstream caspases including caspase 9, thereby commiting the cell to undergo apoptosis.

Host Species: Mouse

Clone: 8CSP03; same as 4.1.20

Isotype: IgG1

Species Reactivity: Human. Others not tested.

Epitope: Not determined

Immunogen: Recombinant full-length human Caspase 8 protein

Molecular Weight: 55 kDa

Positive Control: Jurkat cells

Cellular Localization: Cytoplasmic

Recommended for:

  • Western Blotting
  • Immunoprecipitation (Denatured verified)

Note:

USA: RUO; Int'l: RUO

Specifications

Antigen Caspase 8 (FLICE) Ab-3
Applications Immunoprecipitation, Western Blot
Classification Monoclonal
Clone 8CSP03; same as 4.1.20
Concentration 1mg/mL
Conjugate Unconjugated
Host Species Mouse
Immunogen Recombinant full length human Caspase 8 protein
Quantity 100 μL
Regulatory Status RUO
Research Discipline Apoptosis
Primary or Secondary Primary
Target Species Human
Form Concentrated
Isotype IgG1
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