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  6. Epredia™ Lab Vision™ c-Abl Ab-1 Mouse Monoclonal Antibody, biotin labeled with BSA and azide

Epredia™ Lab Vision™ c-Abl Ab-1 Mouse Monoclonal Antibody, biotin labeled with BSA and azide

Catalog No. MS938B0 Shop All Epredia Products
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100 μL
500 μL
1 mL
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Catalog No. Quantity Form
MS938B0 100 μL Concentrated
MS938B1 500 μL Concentrated
MS938B 1 mL Concentrated
MS938R1 1 mL Prediluted
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Catalog No. MS938B0 Supplier Epredia™ Supplier No. MS938B0

Description

Obtain accurate, reproducible results in immunohistochemistry, western blotting, immunofluorescence, and immunoprecipitation procedures.

The c-Abl proto-oncogene encodes a protein tyrosine kinase that is located in the cytoplasm and nucleus. In chronic myelogenous leukemia and in a subset of acute lymphoblastic leukemias, the c-Abl proto-oncogene undergoes a (9;22) chromosomal translocation producing a novel rearranged chromosome (the Philadelphia chromosome). As the result of the fusion of c-Abl sequences from chromosome 9 to the Bcr gene on chromosome 22. The molecular consequence of this translocation is the generation of a chimeric Bcr/Abl mRNA encoding activated Abl protein tyrosine kinase.

Host Species: Mouse

Clone: 8E9

Isotype: IgG1/γ

Species Reactivity: Human and Mouse. Others not tested.

Epitope: SH2 domain

Immunogen: Recombinant Abl protein

Molecular Weight: 120kDa

Positive Control: HeLa cells or placenta

Cellular Localization: Cytoplasmic and nuclear

Ab-1 reacts with c-Abl p120 and chimeric Bcr/Abl proteins.

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)
  • Western Blotting
  • Immunofluorescence
  • Immunoprecipitation

Note:

USA: RUO; Int'l: RUO

Specifications

Antigen c-Abl Ab-1
Applications Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Classification Monoclonal
Clone 8E9
Concentration 200μg/mL
Conjugate Biotin
Host Species Mouse
Immunogen Recombinant Abl protein
Quantity 100 μL
Regulatory Status RUO
Research Discipline Signal Transduction
Primary or Secondary Primary
Target Species Human, Mouse
Form Concentrated
Isotype IgG1
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