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Epredia™ Lab Vision™ Calponin-1 Rabbit Monoclonal Antibody

Catalog No. RM2102RQ Shop All Epredia Products
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Quantity:
100 μL
1 mL
7 mL
12 mL
Form:
Concentrated
Prediluted
Ready-to-Use
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Catalog No. Quantity Form
RM2102RQ 12 mL Ready-to-Use
RM2102S0 100 μL Concentrated
RM2102S 1 mL Concentrated
RM2102R1 1 mL Prediluted
RM2102R7 7 mL Prediluted
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Catalog No. RM2102RQ Supplier Epredia™ Supplier No. RM2102RQ

Item Discontinued This item has been discontinued by the supplier. Please to view product availability in your area.

Obtain accurate, reproducible results in immunohistochemistry procedures with Epredia™ Calponin-1, Rabbit Monoclonal Antibody.

Calponin, a thin filament associated protein, is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. Calponin is expressed in smooth muscle and tissues containing significant amounts of smooth muscle. Two isoforms of calponin exist whose molecular weights are 34 kDa and 29 kDa. Expression of the 29 kDa form is primarily restricted to muscle of the urogenital tract. The expression of calponin has also been demonstrated in myoepithelial cells from benign and malignant breast lesions. It stains smooth muscle, myoepithelial cells, myofibroblasts, keratinocytes and nerve fibers. It identifies myoepithelial cells in breast lesions, and helps differentiate breast collagenous spherulosis (positive) from adenoid cystic carcinoma. Adenoid cystic carcinoma in salivary gland tumors is calponin positive.

Host Species: Rabbit

Clone: EP798Y

Species Reactivity: Human. Others not known.

Immunogen: A synthetic peptide derived from near the C-terminus of human Calponin-1

Molecular Weight: 29/34 kDa

Positive Control: Breast CA

Cellular Localization: Cytoplasm Myoepithelial cells

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)

Specifications

Antigen Calponin
Applications Immunohistochemistry (Paraffin)
Classification Monoclonal
Clone EP798Y
Conjugate Unconjugated
Host Species Rabbit
Immunogen A synthetic peptide derived from near the C-terminus of human Calponin-1
Quantity 12 mL
Regulatory Status IVD
Research Discipline Cancer and Tumor Biology
Primary or Secondary Primary
Form Ready-to-Use
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