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CD15 Ab-3 Mouse Monoclonal Antibody, Epredia™
Ensure accurate, reproducible results in immunohistochemistry and flow cytometry procedures with Epredia™ CD15 Ab-3, Mouse Monoclonal Antibody.
Supplier: Epredia MS1259RQ
Description
3-fucosyl-N-acetyllactosamine (3-FAL) or CD15 or X-hapten plays a role in mediating phagocytosis, bactericidal activity, and chemotaxis. It is present on >95% of granulocytes including neutrophils and eosinophils and to a lesser degree on monocytes. CD15 is also expressed in Reed-Sternberg cells and some epithelial cells. CD15 antibody is very useful in the identification of Hodgkin's disease. CD15 is occasionally expressed in large cell lymphomas of both B and T phenotypes which otherwise have a quite distinct histological appearance.Host Species: Mouse
Clone: MMA; same as LeuM1
Isotype: IgM/κ
Species Reactivity: Human. Others not tested.
Epitope: Not determined
Immunogen: U937 histiocytic cell line
Molecular Weight: 220kDa
Positive Control: Reed-Sternberg's cells in Hodgkin's lymphoma
Cellular Localization: Membrane and granular paranuclear
Recommended for:
- Immunohistochemistry (Formalin/paraffin)
- Flow Cytometry
Specifications
| CD15 Ab-3 | |
| Monoclonal | |
| — | |
| Mouse | |
| 12 mL | |
| Oncogenesis | |
| Ready-to-Use |
| Flow Cytometry, Immunohistochemistry (Paraffin) | |
| MMA; same as LeuM1 | |
| Unconjugated | |
| U937 histiocytic cell line | |
| IVD | |
| Primary |
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