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Epredia™ Lab Vision™ CD21 Ab-2, Mouse Monoclonal Antibody

Catalog No. MS1086S0 Shop All Epredia Products
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100 μL
500 μL
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7 mL
12 mL
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Catalog No. Quantity Form
MS1086S0 100 μL Concentrated
MS1086S1 500 μL Concentrated
MS1086S 1 mL Concentrated
MS1086R7 7 mL Prediluted
MS1086RQ 12 mL Ready-to-Use
MS1086R1 1 mL Prediluted
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Description

Ensure accurate and reproducible results in immunohistochemistry experiments withEpredia™ CD21 Ab-2, Mouse Monoclonal Antibody.

CD21, also known as CR2, C3d receptor and EBV receptor, is expressed strongly on mature B cells, follicular dentritic cells and weakly on immature thymocytes and T lymphocytes. In B-cell ontogeny, CD21 appears after the pre-B-stage, is maintained during peripheral B-cell development and is lost upon terminal differentiation into plasma cells. CD21 expression is also gradually lost after stimulation of B cells in vitro. CD21 functions as receptor for C3d, C3dg and iC3b Complement components, for EBV and for IFNα. CD21 binds to CD23 and associates with CD19, CD81 and Leu13 to form a large signal-transduction complex involved in B cell activation.

Host Species: Mouse

Clone: 2G9

Isotype: IgG2a

Species Reactivity: Human. Others not tested.

Epitope: Extracellular domain

Immunogen: Recombinant protein encoding the external domain of human CD21

Molecular Weight: 140 kDa

Positive Control: Tonsil

Cellular Localization: Membrane

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)

Specifications

Antigen CD21 Ab-2
Applications Immunohistochemistry (Paraffin)
Classification Monoclonal
Clone 2G9
Conjugate Unconjugated
Host Species Mouse
Immunogen Recombinant protein encoding the external domain of human CD21
Quantity 100 μL
Regulatory Status IVD
Research Discipline B-Cell
Primary or Secondary Primary
Target Species Human
Form Concentrated
Isotype IgG2a
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Safety and Handling

WARNING: Reproductive Harm - www.P65Warnings.ca.gov
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