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CD36/GPIIIb/GPIV Ab-3 Mouse Monoclonal Antibody, Epredia™

Catalog No. MS756P1ABX Shop All Epredia Products
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Quantity:
100 μL
200 μL
500 μL
1 mL
Concentration:
1mg/mL
200μg/mL
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Catalog No. Quantity Concentration
MS756P1ABX 100 μL 1mg/mL
MS756P1 500 μL 200μg/mL
MS756P 1 mL 200μg/mL
MS756PABX 200 μL 1mg/mL
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Description

Ensure accurate, reproducible results in immunohistochemistry , immunofluorescence, flow cytometry and function blocking experiment.

CD36 (also known as platelet glycoprotein IV, OKM5-antigen, or platelet glycoprotein IIIb) acts as a receptor for thrombospondin (TSP), collagen, falciparum malaria parasitized erythrocytes, and sickle erythrocytes. It also functions as a scavenger receptor, mediating macrophage uptake of oxidized low-density lipoprotein (LDL), and apoptotic polymorphonuclear leukocytes (PMN). CD36 plays a role in platelet aggregation, macrophage foam cell development, inflammation, and the tissue ischaemia observed in sickle cell disease and cerebral malaria. Ab-3 blocks adhesion of P. falciparum parasitized red blood cells to CD36 and strongly inhibits collagen-induced platelet aggregation.

Host Species: Mouse

Clone: 185-1G2

Isotype: IgG2a/κ

Species Reactivity: Human. Others not tested.

Epitope: Not determined

Immunogen: Stimulated human leukocytes

Molecular Weight: 88 kDa

Positive Control: Tonsil

Cellular Localization: Membrane

Recommended for:

  • Immunohistochemistry (Frozen only)
  • Western Blotting (Not suitable)
  • Immunofluorescence
  • Flow Cytometry
  • Function Blocking

Note:

USA: RUO; Int'l: RUO

Specifications

Antigen CD36/GPIIIb/GPIV Ab-3
Applications Flow Cytometry, Immunofluorescence, Immunohistochemistry (Frozen)
Classification Monoclonal
Clone 185-1G2
Concentration 1mg/mL
Conjugate Unconjugated
Host Species Mouse
Immunogen Stimulated human leukocytes
Quantity 100 μL
Regulatory Status RUO
Research Discipline Hematopoietic
Primary or Secondary Primary
Target Species Human
Form Concentrated
Isotype IgG2a κ
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