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Epredia™ Lab Vision™ CD8 Ab-1, Mouse Monoclonal Antibody

Catalog No. MS457R1 Shop All Epredia Products
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7 mL
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MS457R1 1 mL Prediluted
MS457R7 7 mL Prediluted
MS457S0 100 μL Concentrated
MS457S1 500 μL Concentrated
MS457S 1 mL Concentrated
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Catalog No. MS457R1 Supplier Epredia™ Supplier No. MS457R1

Description

Obtain accurate, reproducible results in immunohistochemistry experiments with Epredia™ CD8 Ab-1, Mouse Monoclonal Antibody.

CD8 molecule consists of two chains, termed α and Β chain, which are expressed as a disulphide-α β heterdimer or as an alpha α homodimer on T cell subset (cytotoxic/suppressor T cells), thymocytes and NK cells. The majority of CD8+ Tcells expresses CD8 as αβheterodimer. CD8 functions as a coreceptor in concert with TCR for binding the MHC class I/peptide complex. The HIV-2 envelope glycoprotein binds CD8 α chain (but not Β chain).

Host Species: Mouse

Clone: C8/144B

Isotype: IgG1/κ

Species Reactivity: Human. Does not react with rat. Others not known.

Epitope: C-terminal

Immunogen: A 13 amino acid synthetic peptide from the C-terminal cytoplasmic domain of α-chain of human CD8 molecule

Molecular Weight: 32 kDa

Positive Control: Lymph node or tonsil

Cellular Localization: Membrane

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)

General References:

1. Mason DY, et. al. Journal of Clinical Pathology, 1992, 45(12):1084-8.

Specifications

Antigen CD8 Ab-1
Applications Immunohistochemistry (Paraffin)
Classification Monoclonal
Clone C8/144B
Conjugate Unconjugated
Host Species Mouse
Immunogen A 13 amino acid synthetic peptide from the C-terminal cytoplasmic domain of alpha chain of human CD8 molecule
Quantity 1 mL
Regulatory Status IVD
Research Discipline T-Cell
Primary or Secondary Primary
Target Species Human
Form Prediluted
Isotype IgG2a κ
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