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Cyclin D1 Rabbit Monoclonal Antibody, Epredia™
Obtain accurate, reproducible results in immunohistochemistry experiments with Epredia™ Cyclin D1, Rabbit Monoclonal Antibody.
Supplier: Epredia RM2113R1
Description
Cyclin D1 or PRAD-1 or bcl-1 is a key cell cycle regulator. It functions in association with cdk4 and/or cdk6 by phosphorylating the retinoblastoma protein that releases transcription factors to initiate DNA replication. It is a putative proto-oncogene overexpressed in a wide variety of human neoplasms. In lymphoid lesions, with the exception of few rare diseases, it is specific for mantle cell lymphoma (MCL).Host Species: Rabbit
Clone: EPR2241IHC
Isotype: IgG
Species Reactivity: Human. Others not tested.
Immunogen: A synthetic peptide corresponding to residues near the C-terminus of human Cyclin D1
Molecular Weight: 36 kDa
Positive Control: Mantle cell lymphoma
Cellular Localization: Nuclear
Recommended for:
- Immunohistochemistry (Formalin/paraffin)
Specifications
| Cyclin D1 | |
| EPR2241IHC | |
| Ready-to-use for IHC (UVLP) | |
| A synthetic peptide corresponding to residues near the C-terminus of human Cyclin D1 | |
| Primary | |
| Ready-to-Use |
| Immunohistochemistry | |
| Unconjugated | |
| Rabbit | |
| 1 mL | |
| Human |
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