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Cyclin D1 Rabbit Monoclonal Antibody, Epredia™

Catalog No. RM2113R1 Shop All Epredia Products
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RM2113R1 1 mL Ready-to-Use
RM2113R7 7 mL Ready-to-Use
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Catalog No. RM2113R1 Supplier Epredia Supplier No. RM2113R1

Description

Obtain accurate, reproducible results in immunohistochemistry experiments with Epredia™ Cyclin D1, Rabbit Monoclonal Antibody.

Cyclin D1 or PRAD-1 or bcl-1 is a key cell cycle regulator. It functions in association with cdk4 and/or cdk6 by phosphorylating the retinoblastoma protein that releases transcription factors to initiate DNA replication. It is a putative proto-oncogene overexpressed in a wide variety of human neoplasms. In lymphoid lesions, with the exception of few rare diseases, it is specific for mantle cell lymphoma (MCL).

Host Species: Rabbit

Clone: EPR2241IHC

Isotype: IgG

Species Reactivity: Human. Others not tested.

Immunogen: A synthetic peptide corresponding to residues near the C-terminus of human Cyclin D1

Molecular Weight: 36 kDa

Positive Control: Mantle cell lymphoma

Cellular Localization: Nuclear

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)

Specifications

Antigen Cyclin D1
Applications Immunohistochemistry
Clone EPR2241IHC
Conjugate Unconjugated
Formulation Ready-to-use for IHC (UVLP)
Host Species Rabbit
Immunogen A synthetic peptide corresponding to residues near the C-terminus of human Cyclin D1
Quantity 1 mL
Primary or Secondary Primary
Target Species Human
Form Ready-to-Use
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