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Cyclin D1 Rabbit Monoclonal Antibody, Epredia™

Obtain accurate, reproducible results in immunohistochemistry experiments with Epredia™ Cyclin D1, Rabbit Monoclonal Antibody.

Supplier:  Epredia RM2113RQ

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Catalog No. RM2113RQ

Item Discontinued This item has been discontinued by the supplier. Please to view product availability in your area.


Description

Description

Cyclin D1 or PRAD-1 or bcl-1 is a key cell cycle regulator. It functions in association with cdk4 and/or cdk6 by phosphorylating the retinoblastoma protein that releases transcription factors to initiate DNA replication. It is a putative proto-oncogene overexpressed in a wide variety of human neoplasms. In lymphoid lesions, with the exception of few rare diseases, it is specific for mantle cell lymphoma (MCL).

Host Species: Rabbit

Clone: EPR2241IHC

Isotype: IgG

Species Reactivity: Human. Others not tested.

Immunogen: A synthetic peptide corresponding to residues near the C-terminus of human Cyclin D1

Molecular Weight: 36 kDa

Positive Control: Mantle cell lymphoma

Cellular Localization: Nuclear

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)
Specifications

Specifications

Cyclin D1
EPR2241IHC
Rabbit
12 mL
Ready-to-Use
Immunohistochemistry
Unconjugated
A synthetic peptide corresponding to residues near the C-terminus of human Cyclin D1
Primary
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