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  6. Epredia™ Lab Vision™ Cystic Fibrosis Transmembrane Regulator (CFTR) Ab-4 Mouse Monoclonal Antibody, 200μg/mL, BSA and azide

Epredia™ Lab Vision™ Cystic Fibrosis Transmembrane Regulator (CFTR) Ab-4 Mouse Monoclonal Antibody, 200μg/mL, BSA and azide

Catalog No. MS1249PABX Shop All Epredia Products
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Quantity:
100 μL
200 μL
500 μL
1 mL
7 mL
Form:
Concentrated
Prediluted
Concentration:
1mg/mL
200μg/mL
Prediluted
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Catalog No. Quantity Form Concentration
MS1249PABX 200 μL Concentrated 1mg/mL
MS1249P1 500 μL Concentrated 200μg/mL
MS1249P0 100 μL Concentrated 200μg/mL
MS1249P1ABX 100 μL Concentrated 1mg/mL
MS1249P 1 mL Concentrated 200μg/mL
MS1249R1 1 mL Prediluted Prediluted
MS1249R7 7 mL Prediluted Prediluted
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Catalog No. MS1249PABX Supplier Epredia™ Supplier No. MS1249PABX

Description

Obtain accurate, reproducible results in immunohistochemistry, immunofluorescence and immunoprecipitation experiments.

CFTR (cystic fibrosis transmembrane conductance regulator) is composed of two membrane-spanning domains (MSD), two nucleotide-binding domains (NBD), and an R domain. It is structurally similar to multidrug resistance (Mdr1) protein and both are members of the superfamily of ATP-binding cassette (ABC) transporters, also known as traffic ATPases, which are implicated in the movement of various substrates. The CFTR protein is a small conductance adenosine 3',5'-cyclic monophosphate (cAMP)-activated chloride ion channel found in the apical membranes of epithelia within the pancreas, airway, intestine, bile duct, sweat gland, and male genital ducts. CFTR is a valuable marker of human pancreatic duct cell development and differentiation.

Host Species: Mouse

Clone: M3A7

Isotype: IgG1

Species Reactivity: Human, Mouse and Rat. Others not known.

Epitope: aa 1370-1380

Immunogen: Recombinant protein encoding NBF2 domain of human CFTR

Molecular Weight: 165-170 kDa

Positive Control: Pancreas

Cellular Localization: Membrane

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)
  • Western Blotting (Not verified)
  • Immunofluorescence
  • Immunoprecipitation

Note:

USA: RUO; Int'l: RUO

Specifications

Antigen Cystic Fibrosis Transmembrane Regulator (CFTR) Ab-4
Applications Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation
Classification Monoclonal
Clone M3A7
Concentration 1mg/mL
Conjugate Unconjugated
Host Species Mouse
Immunogen Recombinant protein encoding NBF2 domain of human CFTR
Quantity 200 μL
Regulatory Status RUO
Primary or Secondary Primary
Target Species Human, Mouse, Rat
Form Concentrated
Isotype IgG1
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