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  6. Epredia™ Lab Vision™ Cytokeratin 17 Ab-1, Mouse Monoclonal Antibody

Epredia™ Lab Vision™ Cytokeratin 17 Ab-1, Mouse Monoclonal Antibody

Catalog No. MS489S Shop All Epredia Products
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100 μL
500 μL
1 mL
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Concentrated
Prediluted
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Catalog No. Quantity Form
MS489S 1 mL Concentrated
MS489S0 100 μL Concentrated
MS489S1 500 μL Concentrated
MS489R1 1 mL Prediluted
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Catalog No. MS489S Supplier Epredia™ Supplier No. MS489S

Description

Obtain accurate, reproducible results in immunohistochemistry and immunofluorescence experiments with Epredia™ Cytokeratin 17 Ab-1, Mouse Monoclonal Antibody.

The type I keratin 17 (K17) shows a peculiar localization in human epithelial appendages including hair follicles, which undergo a growth cycle throughout adult life. Additionally K17 is induced, along with K6 and K16, early after acute injury to human skin. Predominant expression of K17 and the frequent expression of K8 and K19, with little K6/K16 and K1/K10 expression are the characteristic features of basal cell carcinomas (BCC), suggesting that BCC is differentiated towards undifferentiated follicular epithelia, most probably hair bulge cells.

Host Species: Mouse

Clone: E3

Isotype: IgG2b/κ

Species Reactivity: Human and Rat. Others not known.

Epitope: Not determined

Immunogen: Cytokeratin preparation from rat enterocytes

Molecular Weight: 46 kDa

Positive Control: Squamous cell CA, Skin

Cellular Localization: Cytoplasmic

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)
  • Immunofluorescence

Specifications

Antigen Cytokeratin 17 Ab-1
Applications Immunofluorescence, Immunohistochemistry (Paraffin)
Classification Monoclonal
Clone E3
Conjugate Unconjugated
Host Species Mouse
Immunogen Keratin preparation from rat enterocytes
Purification Method Squamous cell CA, skin
Quantity 1 mL
Regulatory Status IVD
Research Discipline Cytoskeletal Protein
Primary or Secondary Primary
Target Species Human, Rat
Form Concentrated
Isotype IgG2b κ
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