Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. Antibodies
  4. Primary Antibodies
  5. All Primary Antibodies
  6. DOG1 Mouse Monoclonal Antibody, Epredia™

DOG1 Mouse Monoclonal Antibody, Epredia™

Catalog No. MS1933R7 Shop All Epredia Products
Change view
Click to view available options
Quantity:
100 μL
1 mL
7 mL
12 mL
Form:
Purified
Ready-to-Use
5 product options available for selection
Product selection table with 5 available options. Use arrow keys to navigate and Enter or Space to select.
Catalog No. Quantity Form
MS1933R7 7 mL Ready-to-Use
MS1933P0 100 μL Purified
MS1933P 1 mL Purified
MS1933R1 1 mL Ready-to-Use
MS1933RQ 12 mL Ready-to-Use
Use arrow keys to navigate between rows. Press Enter or Space to select a product option. 5 options available.
5 options
Catalog No. MS1933R7 Supplier Epredia Supplier No. MS1933R7
Only null left
Add to Cart
Add to Cart

Description

Obtain accurate, reproducible results in immunohistochemistry experiments with Epredia™ Dog1, Mouse Monoclonal Antibody.

DOG1 is a cell surface protein of unknown function selectively expressed in gastrointestinal stromal tumors (GIST). Among GIST cases with KIT mutations the DOG1 antibody identified 11% more cases than c-Kit antibody1. DOG1 identifies vast majority of both c-Kit negative and PDGFRA mutated GIST cases that may still benefit from imatinib mesylate (Gleevac), an inhibitor of the kit tyrosine kinase2. In addition, DOG1 immunoreactivity is seen in fewer cases of mesanchymal, epithelial tumors and melanomas when compared with c-Kit. The use of this highly sensitive and specific novel marker will increase the accuracy of GIST diagnosis.

Host Species: Mouse

Clone: 1.1

Isotype: Unknown

Species Reactivity: Human. Others not known.

Immunogen: Synthetic peptide of human DOG1

Molecular Weight: 78 kDa

Positive Control: Gastrointestinal Stromal Tumors

Cellular Localization: Cytoplasmic and Membrane

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)

Specifications

Antigen Dog1
Applications Immunohistochemistry
Clone 1.1
Concentration 200μg/mL
Conjugate Unconjugated
Host Species Mouse
Immunogen Synthetic peptide of human Dog1
Quantity 7 mL
Primary or Secondary Primary
Target Species Human
Form Ready-to-Use
Show More Show Less
Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.