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  6. Epidermal Growth Factor Receptor/EGFR Ab-10 Mouse Monoclonal Antibody, Epredia™

Epidermal Growth Factor Receptor/EGFR Ab-10 Mouse Monoclonal Antibody, Epredia™

Catalog No. MS378P1 Shop All Epredia Products
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Quantity:
100 μL
200 μL
500 μL
1 mL
Conjugate:
Biotin
Unconjugated
Form:
Concentrated
Prediluted
Concentration:
1mg/mL
200μg/mL
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Catalog No. Quantity Conjugate Form Concentration
MS378P1 500 μL Unconjugated Concentrated 200μg/mL
MS378B0 100 μL Biotin Concentrated 200μg/mL
MS378B1 500 μL Biotin Concentrated 200μg/mL
MS378P0 100 μL Unconjugated Concentrated 200μg/mL
MS378P1ABX 100 μL Unconjugated Concentrated 1mg/mL
MS378PABX 200 μL Unconjugated Concentrated 1mg/mL
MS378R1 1 mL Unconjugated Prediluted -
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Catalog No. MS378P1 Supplier Epredia Supplier No. MS378P1
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Description

Ensure accurate, reproducible results in immunohistochemistry, western blotting and immunoprecipitation experiments.

EGFR is a type I receptor tyrosine kinase with sequence homology to erbB-1, -2, -3 -4 or HER-1, -2, -3 -4. It binds to Epidermal Growth Factor (EGF), Transforming Growth Factor-a (TGF-a), Heparin-binding EGF (HB-EGF), amphiregulin, βcellulin and epiregulin. EGFR is overexpressed in tumors of breast, brain, bladder, lung, gastric, head & neck, esophagus, cervix, vulva, ovary, and endometrium. It is predominantly present in squamous cell carcinomas.

Host Species: Mouse

Clone: 111.6

Isotype: IgG1

Species Reactivity: Human. Not mouse and rat.

Epitope: Extracellular domain

Immunogen: Extracellular domain of human recombinant EGFR protein

Molecular Weight: 170 kDa (wild type) and 145 kDa (vIII variant)

Positive Control: A431 cells; Skin, Placenta or Squamous cell CA

Cellular Localization: Membrane

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)
  • Western Blotting
  • Immunoprecipitation (Native only)
  • Effect on EGF Binding (Inhibitory)

Note:

USA: RUO; Int'l: RUO

Specifications

Antigen Epidermal Growth Factor Receptor/EGFR Ab-10
Applications Immunohistochemistry (Paraffin), Immunoprecipitation
Classification Monoclonal
Clone 111.6
Concentration 200μg/mL
Conjugate Unconjugated
Host Species Mouse
Immunogen Extracellular domain of human recombinant EGFR protein
Quantity 500 μL
Regulatory Status RUO
Research Discipline EGFR Family
Primary or Secondary Primary
Target Species Human
Form Concentrated
Isotype IgG1
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