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  6. Epidermal Growth Factor Receptor/EGFR Ab-10 Mouse Monoclonal Antibody, Epredia™

Epidermal Growth Factor Receptor/EGFR Ab-10 Mouse Monoclonal Antibody, Epredia™

Catalog No. MS378R1 Shop All Epredia Products
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Quantity:
100 μL
200 μL
500 μL
1 mL
Conjugate:
Biotin
Unconjugated
Form:
Concentrated
Prediluted
Concentration:
1mg/mL
200μg/mL
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Catalog No. Quantity Conjugate Form Concentration
MS378R1 1 mL Unconjugated Prediluted -
MS378B0 100 μL Biotin Concentrated 200μg/mL
MS378P1 500 μL Unconjugated Concentrated 200μg/mL
MS378B1 500 μL Biotin Concentrated 200μg/mL
MS378P0 100 μL Unconjugated Concentrated 200μg/mL
MS378P1ABX 100 μL Unconjugated Concentrated 1mg/mL
MS378PABX 200 μL Unconjugated Concentrated 1mg/mL
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Catalog No. MS378R1 Supplier Epredia Supplier No. MS378R1

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Description

Ensure accurate, reproducible results in immunohistochemistry, western blotting and immunoprecipitation experiments.

EGFR is a type I receptor tyrosine kinase with sequence homology to erbB-1, -2, -3 -4 or HER-1, -2, -3 -4. It binds to Epidermal Growth Factor (EGF), Transforming Growth Factor-a (TGF-a), Heparin-binding EGF (HB-EGF), amphiregulin, βcellulin and epiregulin. EGFR is overexpressed in tumors of breast, brain, bladder, lung, gastric, head & neck, esophagus, cervix, vulva, ovary, and endometrium. It is predominantly present in squamous cell carcinomas.

Host Species: Mouse

Clone: 111.6

Isotype: IgG1

Species Reactivity: Human. Not mouse and rat.

Epitope: Extracellular domain

Immunogen: Extracellular domain of human recombinant EGFR protein

Molecular Weight: 170 kDa (wild type) and 145 kDa (vIII variant)

Positive Control: A431 cells; Skin, Placenta or Squamous cell CA

Cellular Localization: Membrane

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)
  • Western Blotting
  • Immunoprecipitation (Native only)
  • Effect on EGF Binding (Inhibitory)

Note:

USA: RUO; Int'l: RUO

Specifications

Antigen Epidermal Growth Factor Receptor/EGFR Ab-10
Applications Immunohistochemistry (Paraffin), Immunoprecipitation
Classification Monoclonal
Clone 111.6
Conjugate Unconjugated
Formulation Ready-to-use for IHC (UVLP)
Host Species Mouse
Immunogen Extracellular domain of human recombinant EGFR protein
Quantity 1 mL
Regulatory Status RUO
Research Discipline EGFR Family
Primary or Secondary Primary
Target Species Human
Form Prediluted
Isotype IgG1
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