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Epredia™ Lab Vision™ Estrogen Receptor Ab-14, Mouse Monoclonal Antibody

Catalog No. MS750S Shop All Epredia Products
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1 mL
7 mL
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MS750S 1 mL Concentrated
MS750S0 100 μL Concentrated
MS750S1 500 μL Concentrated
MS750R7 7 mL Prediluted
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Description

Ensure accurate, reproducible results in immunohistochemistry and western blotting experiments with Epredia™ Estrogen Receptor Ab-14, Mouse Monoclonal Antibody.

The ER gene consists of more than 140kb of genomic DNA divided into 8 exons and is translated into a protein with six functionally discrete domains required for transcription activation function, binding to estrogen response element (ERE) constitutive dimerization, binding to heat shock proteins, and ligand recognition. The ER is an important regulator of growth and differentiation in the mammary gland. Presence of ER in breast tumors indicates an increased likelihood of response to anti-estrogen (e.g. tamoxifen) therapy.

Host Species: Mouse

Clone: 1D5 + 6F11

Isotype: IgG1 + IgG1/κ

Species Reactivity: Human and Rat. Others not known.

Epitope: Not determined

Immunogen: Recombinant human estrogen receptor protein

Molecular Weight: 67 kDa

Positive Control: MCF-7 cells, Breast CA

Cellular Localization: Nuclear

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)
  • Western Blotting

Specifications

Antigen Estrogen Receptor Ab-14
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Monoclonal
Clone 1D5 + 6F11
Conjugate Unconjugated
Dilution WB 1:50-1:100 for 2h RT; IH 1:100-1:200 for 30 min
Host Species Mouse
Immunogen Recombinant human estrogen receptor protein
Quantity 1 mL
Regulatory Status ASR, IVD
Research Discipline Oncogenesis
Primary or Secondary Primary
Target Species Human, Rat
Content And Storage Store vial at 4deg.C. When stored at 2 to 8deg.C,
Form Concentrated
Isotype IgG1
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Safety and Handling

WARNING: Reproductive Harm - www.P65Warnings.ca.gov
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