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Estrogen Receptor Ab-16 Rabbit Polyclonal Antibody, Epredia™

Catalog No. RB1493P1ABX Shop All Epredia Products
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Quantity:
100 μL
500 μL
1 mL
7 mL
Form:
Concentrated
Prediluted
Formulation:
Purified w/o BSA and Azide
Purified with BSA and Azide
Ready-to-use
Ready-to-use for IHC (UVLP)
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Catalog No. Quantity Form Formulation
RB1493P1ABX 500 μL Concentrated Purified w/o BSA and Azide
RB1493P0 100 μL Concentrated Purified with BSA and Azide
RB1493P1 500 μL Concentrated Purified with BSA and Azide
RB1493P 1 mL Concentrated Purified with BSA and Azide
RB1493PABX 1 mL Concentrated Purified w/o BSA and Azide
RB1493R1 1 mL Prediluted Ready-to-use for IHC (UVLP)
RB1493R7 7 mL Prediluted Ready-to-use
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Catalog No. RB1493P1ABX Supplier Epredia Supplier No. RB1493P1ABX

Description

Obtain accurate, reproducible results in immunohistochemistry, western blotting and immunoprecipitation experiments.

The ER gene consists of more than 140kb of genomic DNA divided into 8 exons and is translated into a protein with six functionally discrete domains required for transcription activation function, binding to estrogen response element (ERE) constitutive dimerization, binding to heat shock proteins, and ligand recognition. ER is an important regulator of growth and differentiation in the mammary gland. Presence of ER in breast tumors indicates an increased likelihood of response to anti-estrogen (e.g. tamoxifen) therapy.

Host Species: Rabbit

Isotype: IgG

Species Reactivity: Human, Mouse and Hamster. Does not react with rat. Others not known.

Epitope: C-terminal

Immunogen: A synthetic peptide derived from the C-terminus of human estrogen receptor, α protein

Molecular Weight: 67 kDa

Positive Control: MCF-7 cells, Breast CA

Cellular Localization: Nuclear

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)
  • Western Blotting
  • Immunoprecipitation (Denatured verified)
  • Gel Supershift (Not verified)

Note:

USA: RUO; Int'l: RUO

Specifications

Antigen Estrogen Receptor Ab-16
Applications Immunoprecipitation, Western Blot
Classification Polyclonal
Concentration 1mg/mL
Conjugate Unconjugated
Formulation Purified w/o BSA and Azide
Host Species Rabbit
Immunogen A synthetic peptide derived from the C-terminus of human estrogen receptor, alpha protein
Quantity 500 μL
Regulatory Status RUO
Research Discipline Steroids Hormones and Growth Factors
Primary or Secondary Primary
Target Species Hamster, Human
Form Concentrated
Isotype IgG
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