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Estrogen Receptor (SP1) Rabbit Monoclonal Antibody, Epredia™

Catalog No. RM9101S0 Shop All Epredia Products
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Quantity:
100 μL
500 μL
1 mL
7 mL
12 mL
Conjugate:
Unconjugated
Form:
Concentrated
Prediluted
Ready-to-Use
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Catalog No. Quantity Conjugate Form
RM9101S0 100 μL Unconjugated Concentrated
RM9101S1 500 μL Unconjugated Concentrated
RM9101S 1 mL Unconjugated Concentrated
RM9101R7 7 mL Unconjugated Prediluted
RM9101RQ 12 mL Unconjugated Ready-to-Use
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Catalog No. RM9101S0 Supplier Epredia Supplier No. RM9101S0

Description

Ensure accurate, reproducible results in immunohistochemistry and western blotting experiments with Epredia™ Estrogen Receptor (SP1), Rabbit Monoclonal Antibody.

Recognizes a protein of 67 kDa, which is identified as estrogen receptor (ER) alpha. The ER gene consists of more than 140kb of genomic DNA divided into 8 exons, and is translated into a protein with six functionally discrete domains, labeled A through F. This antibody strongly stains the nucleus of epithelial cells in breast carcinomas. The ER is an important regulator of growth and differentiation in the mammary gland. Presence of ER in breast tumors indicates an increased likelihood of response to anti-estrogen (e.g. tamoxifen) therapy.

Host Species: Rabbit

Clone: SP1

Isotype: IgG

Species Reactivity: Human, Mouse and Hamster. Others not tested.

Epitope: C-terminus

Immunogen: Synthetic peptide derived from C-terminal of human estrogen receptor

Molecular Weight: 67 kDa

Positive Control: Breast CA, MCF-7 cells

Cellular Localization: Nuclear

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)
  • Western Blotting
  • Immunofluorescence (Not verified)
  • Flow Cytometery (Not verified)

Specifications

Antigen Estrogen Receptor (SP1)
Applications Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Monoclonal
Clone SP1
Conjugate Unconjugated
Host Species Rabbit
Immunogen Synthetic peptide derived from C-terminal of human estrogen receptor
Quantity 100 μL
Regulatory Status IVD
Research Discipline Steroids Hormones and Growth Factors
Primary or Secondary Primary
Target Species Hamster, Human, Mouse
Form Concentrated
Isotype IgG
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