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Epredia™ Lab Vision™ GRP94 Rabbit Polyclonal Antibody with BSA and azide

Catalog No. RB10642P0 Shop All Epredia Products
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Catalog No. Quantity Form
RB10642P0 100 μL Concentrated
RB10642P1 500 μL Concentrated
RB10642P 1 mL Concentrated
RB10642R1 1 mL Prediluted
RB10642R7 7 mL Prediluted
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Catalog No. RB10642P0 Supplier Epredia™ Supplier No. RB10642P0

Description

Ensure accurate, reproducible results in immunohistochemistry experiments with Epredia™ GRP94, Rabbit Polyclonal Antibody.

Heat shock protein (HSP) molecular chaperones are environmental stress inducible gene products. The human HSP 90 family consists of 17 genes classified into four classes: HSP90AA, HSP90AB, HSP90B and TRAP. HSP 90 family members guide the normal folding, intracellular disposition and proteolytic turnover of many key regulators of cell growth, differentiation and survival. GRP 94, glucose regulated protein 94 kDa, a HSP90 family member, (also known as tumor rejection antigen 1 (TRA1), ECGP and GP96), localizes to the ER, is highly expressed in BGC-823 human gastric carcinoma cells and is upregulated in human endothelial cells in response to hypoxia by HIF-1. TRAP1 (TNF receptor-associated protein 1), also designated HSP 75 is a mitochondrial matrix component that plays a role in the induction of apoptosis in response to reactive oxygen species.

Host Species: Rabbit

Species Reactivity: Human. Others not known.

Epitope: C-terminal

Immunogen: Synthetic peptide corresponding to C-terminal of human GRP94

Molecular Weight: 94 kDa

Positive Control: Breast CA

Cellular Localization: Cytoplasmic

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)

Note:

USA: RUO; Int'l: RUO

Specifications

Antigen GRP94
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 200µg/mL
Conjugate Unconjugated
Host Species Rabbit
Immunogen Synthetic peptide corresponding to C-terminal of human GRP94
Purification Method Breast CA
Quantity 100 μL
Regulatory Status RUO
Research Discipline Cancer and Tumor Biology
Primary or Secondary Primary
Target Species Human
Form Concentrated
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