Epredia™ Lab Vision™ HER-2/c-erB-2/neu Rabbit Monoclonal Antibody

Recommended for Immunohistochemistry (Formalin/paraffin), Epredia™ HER-2/c-erB-2/neu, Rabbit Monoclonal Antibody is part of a comprehensive antibody portfolio. Studies show rabbit monoclonal antibodies are more sensitive and specific than other available markers.

Supplier:  Epredia™ RM9103R7A

Catalog No. RM9103R7

Description

c-erbB-2 is a receptor tyrosine kinase of the c-erbB family. It is closely related in structure to the epidermal growth factor receptor. c-erbB-2 oncoprotein is detectable in a proportion of breast and other adenocarconomas, as well as transitional cell carcinomas. In the case of breast cancer, expression determined by immunohistochemistry has been shown to be associated with poor prognosis.

Host Species: Rabbit

Clone: SP3

Isotype: IgG

Species Reactivity: Human. Others not tested.

Epitope: Extracellular domain

Immunogen: Recombinant protein encoding extracellular domain of human HER-2

Molecular Weight: 185 kDa

Positive Control: Breast CA

Cellular Localization: Membrane

Recommended for:

• Immunohistochemistry (Formalin/paraffin)

Specifications

• Antigen: HER-2/c-erB-2/neu
• Classification: Monoclonal
• Conjugate: Unconjugated
• Immunogen: Recombinant protein encoding extracellular domain of human HER-2
• Regulatory Status: IVD
• Primary or Secondary: Primary
• Form: Prediluted

• Applications: Immunohistochemistry (Paraffin)
• Clone: SP3
• Host Species: Rabbit
• Quantity: 7 mL
• Research Discipline: Oncogenesis
• Target Species: Human
• Isotype: IgG