Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. Antibodies
  4. Primary Antibodies
  5. All Primary Antibodies
  6. HER-2/c-erbB-2/neu Ab-4 Mouse Monoclonal Antibody, Epredia™

HER-2/c-erbB-2/neu Ab-4 Mouse Monoclonal Antibody, Epredia™

Catalog No. MS301B Shop All Epredia Products
Change view
Click to view available options
Quantity:
100 μL
200 μL
500 μL
1 mL
Conjugate:
Biotin
Unconjugated
Concentration:
1mg/mL
200μg/mL
8 product options available for selection
Product selection table with 8 available options. Use arrow keys to navigate and Enter or Space to select.
Catalog No. Quantity Conjugate Concentration
MS301B 1 mL Biotin 200μg/mL
MS301P0 100 μL Unconjugated 200μg/mL
MS301P1 500 μL Unconjugated 200μg/mL
MS301P 1 mL Unconjugated 200μg/mL
MS301B0 100 μL Biotin 200μg/mL
MS301B1 500 μL Biotin 200μg/mL
MS301P1ABX 100 μL Unconjugated 1mg/mL
MS301PABX 200 μL Unconjugated 1mg/mL
Use arrow keys to navigate between rows. Press Enter or Space to select a product option. 8 options available.
8 options
Catalog No. MS301B Supplier Epredia Supplier No. MS301B
Only null left
Add to Cart
Add to Cart

Description

Provide accurate, reproducible results with the Epredia™ HER-2/c-erbB-2/neu Ab-4, Mouse Monoclonal Antibody.

c-erbB-2, second member (c-erbB-2/HER-2/neu) of the c-erbB family is a receptor tyrosine kinase. It exhibits extracellular domains with two cysteine-rich sequences, and a cytoplasmic tyrosine kinase domain flanked by large hydrophilic tails that carry several tyrosine autophosphorylation sites. Approximately 25% of primary breast and ovarian tumors were found to overexpress the protein

Host Species: Mouse

Clone: N12

Isotype: IgG1

Species Reactivity: Human. Does not react with mouse and rat. Others not tested.

Epitope: Extracellular domain

Immunogen: Intact SKBR-3 breast cancer cells

Molecular Weight: 185 kDa

Positive Control: SKBR-3 cells, or Breast CA

Cellular Localization: Membrane

Recommended for:

  • Immunofluorescence
  • Immunoprecipitation (Not suitable)
  • Inhibits Tumor Growth (∽90%)
  • Inhibits Cell Proliferation
  • Effect on HER-2 Internalization (Moderate)
  • Electron Microscopy

Note:

USA: RUO; Int'l: RUO

Specifications

Antigen HER-2/c-erbB-2/neu Ab-4
Applications Immunofluorescence, Immunohistochemistry (Frozen)
Classification Monoclonal
Clone N12
Concentration 200μg/mL
Conjugate Biotin
Host Species Mouse
Immunogen Intact SKBR-3 breast cancer cells
Quantity 1 mL
Regulatory Status RUO
Research Discipline EGFR Family
Primary or Secondary Primary
Target Species Human
Form Concentrated
Isotype IgG1
Show More Show Less

Safety and Handling

WARNING: Reproductive Harm - www.P65Warnings.ca.gov
Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.