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  6. HER-2/c-erbB-2/neu Ab-5 Mouse Monoclonal Antibody, Epredia™

HER-2/c-erbB-2/neu Ab-5 Mouse Monoclonal Antibody, Epredia™

Catalog No. MS302P0 Shop All Epredia Products
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Quantity:
100 μL
200 μL
500 μL
1 mL
Concentration:
1mg/mL
200μg/mL
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Catalog No. Quantity Concentration
MS302P0 100 μL 200μg/mL
MS302P1ABX 100 μL 1mg/mL
MS302P1 500 μL 200μg/mL
MS302P 1 mL 200μg/mL
MS302PABX 200 μL 1mg/mL
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Catalog No. MS302P0 Supplier Epredia Supplier No. MS302P0

Description

Provide accurate, reproducible results with the Epredia™ HER-2/c-erbB-2/neu Ab-5, Mouse Monoclonal Antibody.

c-erbB-2 is a receptor tyrosine kinase. It exhibits extracellular domains with two cysteine-rich sequences, and a cytoplasmic tyrosine kinase domain flanked by large hydrophilic tails that carry several tyrosine autophosphorylation sites. Approximately 25% of primary breast and ovarian tumors were found to overexpress the protein

Host Species: Mouse

Clone: N24

Isotype: IgG1

Species Reactivity: Human. Does not react with mouse and rat. Others not tested.

Epitope: Extracellular domain

Immunogen: Intact SKBR-3 breast cancer cells

Molecular Weight: 185 kDa

Positive Control: SKBR-3 cells, or Breast CA

Cellular Localization: Membrane

Recommended for:

  • Immunofluorescence
  • Immunoprecipitation
  • Accelerates (∽50%) HER-2 Internalization
  • Inhibits (∽80%) Tumorigenic Cell Growth

Note:

USA: RUO; Int'l: RUO

Specifications

Antigen HER-2/c-erbB-2/neu Ab-5
Applications Immunofluorescence, Immunoprecipitation
Classification Monoclonal
Clone N24
Concentration 200μg/mL
Conjugate Unconjugated
Host Species Mouse
Immunogen Intact SKBR-3 breast cancer cells
Quantity 100 μL
Regulatory Status RUO
Research Discipline EGFR Family
Primary or Secondary Primary
Target Species Human
Form Concentrated
Isotype IgG1
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