Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
Learn More
HER-2/c-erbB-2/neu Ab-5 Mouse Monoclonal Antibody, Epredia™
Provide accurate, reproducible results with the Epredia™ HER-2/c-erbB-2/neu Ab-5, Mouse Monoclonal Antibody.
Supplier: Epredia MS302P1ABX
Description
c-erbB-2 is a receptor tyrosine kinase. It exhibits extracellular domains with two cysteine-rich sequences, and a cytoplasmic tyrosine kinase domain flanked by large hydrophilic tails that carry several tyrosine autophosphorylation sites. Approximately 25% of primary breast and ovarian tumors were found to overexpress the proteinHost Species: Mouse
Clone: N24
Isotype: IgG1
Species Reactivity: Human. Does not react with mouse and rat. Others not tested.
Epitope: Extracellular domain
Immunogen: Intact SKBR-3 breast cancer cells
Molecular Weight: 185 kDa
Positive Control: SKBR-3 cells, or Breast CA
Cellular Localization: Membrane
Recommended for:
- Immunofluorescence
- Immunoprecipitation
- Accelerates (∽50%) HER-2 Internalization
- Inhibits (∽80%) Tumorigenic Cell Growth
Note:
USA: RUO; Int'l: RUO
Specifications
| HER-2/c-erbB-2/neu Ab-5 | |
| Monoclonal | |
| 1mg/mL | |
| Mouse | |
| 100 μL | |
| EGFR Family | |
| Human | |
| IgG1 |
| Immunofluorescence, Immunoprecipitation | |
| N24 | |
| Unconjugated | |
| Intact SKBR-3 breast cancer cells | |
| RUO | |
| Primary | |
| Concentrated |
Safety and Handling
WARNING: Reproductive Harm - www.P65Warnings.ca.gov
Product Content Correction
Your input is important to us. Please complete this form to provide feedback related to the content on this product.
Product Title
Spot an opportunity for improvement?Share a Content Correction