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HER-2/c-erbB-2/neu Ab-8 Mouse Monoclonal Antibody, Epredia™

Catalog No. MS325B1 Shop All Epredia Products
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Quantity:
100 μL
200 μL
500 μL
1 mL
Conjugate:
Biotin
Unconjugated
Concentration:
1mg/mL
200μg/mL
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Catalog No. Quantity Conjugate Concentration
MS325B1 500 μL Biotin 200μg/mL
MS325B0 100 μL Biotin 200μg/mL
MS325B 1 mL Biotin 200μg/mL
MS325P1 500 μL Unconjugated 200μg/mL
MS325P1ABX 100 μL Unconjugated 1mg/mL
MS325P0 100 μL Unconjugated 200μg/mL
MS325P 1 mL Unconjugated 200μg/mL
MS325PABX 200 μL Unconjugated 1mg/mL
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Catalog No. MS325B1 Supplier Epredia Supplier No. MS325B1
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Recommended for Immunohistochemistry, Western Blotting and Immunoprecipitation (Native and Denatured), Epredia™ HER-2/c-erbB-2/neu Ab-8, Mouse Monoclonal Antibody provides accurate, reproducible results.

c-erbB-2 is a receptor tyrosine kinase. It exhibits extracellular domains with two cysteine-rich sequences, and a cytoplasmic tyrosine kinase domain flanked by large hydrophilic tails that carry several tyrosine autophosphorylation sites. Approximately 25% of primary breast and ovarian tumors were found to overexpress the protein. The c-erbB-2 protein is overexpressed in a variety of carcinomas especially those of breast and ovary.

Host Species: Mouse

Clone: e2-4001

Isotype: IgG1

Species Reactivity: Human, Mouse and Rat. Others not tested.

Epitope: Cytoplasmic domain

Immunogen: Cytoplasmic domain of recombinant human HER-2/c-erbB-2 oncoprotein

Molecular Weight: 185 kDa

Positive Control: SKBR-3 cells, or T47D cells, or Breast CA

Cellular Localization: Membrane

Recommended for:

  • Immunohistochemistry
  • Western Blotting
  • Immunoprecipitation (Native and Denatured)

Note:

USA: RUO; Int'l: RUO

Specifications

Antigen HER-2/c-erbB-2/neu Ab-8
Applications Immunoprecipitation
Classification Monoclonal
Clone e2-4001
Concentration 200μg/mL
Conjugate Biotin
Host Species Mouse
Immunogen Cytoplasmic domain of recombinant human c-erbB-2/HER-2 oncoprotein
Quantity 500 μL
Regulatory Status RUO
Research Discipline Oncogenesis
Primary or Secondary Primary
Target Species Human, Mouse, Rat
Form Concentrated
Isotype IgG1
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