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Epredia™ Lab Vision™ HER-2/c-erbB-2/neu Rabbit Monoclonal Antibody supernatant
Recommended for Immunohistochemistry (Formalin/paraffin), Epredia™ HER-2/c-erbB-2/neu, Rabbit Monoclonal Antibody is part of a comprehensive antibody portfolio. Studies show rabbit monoclonal antibodies are more sensitive and specific than other available markers.
$6972.00
Specifications
Antigen | HER-2/c-erbB-2/neu |
---|---|
Clone | EP1045Y |
Applications | Immunohistochemistry |
Conjugate | Unconjugated |
Host Species | Rabbit |
Description
HER2 gene encodes a transmembrane glycoprotein with tyrosine kinase activity. It is closely related in structure to the epidermal growth factor receptor c-erbB-3/HER3/neu oncoprotein. The protein is detectable in a subset of breast and other carcinomas (urinary bladder, stomach, lung, endometrium and ovary). In the case of breast cancer, over expression determined by immunohistochemistry has been shown to be associated with poor prognosis and an indication to initiate trastuzumab/herceptin therapy.Host Species: Rabbit
Clone: EP1045Y
Isotype: IgG
Species Reactivity: Human. Others not tested.
Epitope: Not determined
Immunogen: A synthetic peptide corresponding to the c-terminus of human Her2
Molecular Weight: 185 kDa
Positive Control: Breast carcinomas
Cellular Localization: Cell membrane
Recommended for:
- Immunohistochemistry (Formalin/paraffin)
Specifications
HER-2/c-erbB-2/neu | |
Immunohistochemistry | |
Rabbit | |
Primary |
EP1045Y | |
Unconjugated | |
A synthetic peptide corresponding to the c-terminus of human Her2 |
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