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  6. IGF-1R (α-subunit) Ab-4 Mouse Monoclonal Antibody, Epredia™

IGF-1R (α-subunit) Ab-4 Mouse Monoclonal Antibody, Epredia™

Catalog No. MS644P0 Shop All Epredia Products
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Quantity:
100 μL
200 μL
500 μL
1 mL
Concentration:
1mg/mL
200μg/mL
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Catalog No. Quantity Concentration
MS644P0 100 μL 200μg/mL
MS644P1 500 μL 200μg/mL
MS644P 1 mL 200μg/mL
MS644P1ABX 100 μL 1mg/mL
MS644PABX 200 μL 1mg/mL
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Catalog No. MS644P0 Supplier Epredia Supplier No. MS644P0

Description

Epredia™ IGF-1R (α-Subunit) Ab-4, Mouse Monoclonal Antibody provides accurate, reproducible results.

IGF-1R (Insulin-like Growth Factor-1 Receptor) consists of α- and Β-subunits, which are disulfide-linked in a Β-α-α-Β configuration in the mature receptor. The α-subunit is completely extracellular, while the Β-subunit spans the membrane and the intracellular portion has intrinsic tyrosine kinase activity.

Host Species: Mouse

Clone: 24-60

Isotype: IgG2a/κ

Species Reactivity: Human. Weakly reacts with Rabbit and Pig (Ab-2 is better). Does not react with rat.

Epitope: aa 184-283

Immunogen: IGF-1R/3T3 mouse fibroblasts transfected with human type I IGF-receptor cDNA

Molecular Weight: 125kDa

Positive Control: Placenta or Breast CA

Cellular Localization: Membrane Ab-4 is excellent for immunoprecipitation of alpha-subunit of IGF-1R.

Recommended for:

  • Western Blotting (Not suitable)
  • Immunoprecipitation
  • Acts as a Weak IGF-like Agonist in Bioassays (Thymidine incorporation into DNA)
  • Substantially (>80%) Inhibits IGF-1 Binding

Note:

USA: RUO; Int'l: RUO

Specifications

Antigen IGF-1R (alpha-Subunit) Ab-4
Applications Immunoprecipitation
Classification Monoclonal
Clone 24-60
Concentration 200μg/mL
Conjugate Unconjugated
Host Species Mouse
Immunogen IGF-1R/3T3 mouse fibroblasts transfected with human type I IGF-receptor cDNA
Quantity 100 μL
Regulatory Status RUO
Research Discipline Neuroscience
Primary or Secondary Primary
Target Species Human
Form Concentrated
Isotype IgG2a κ
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